Evidence map›Paper›PMID 41488933›Full record

ReviewFrontiers in drug safety and regulation2025

A narrative review on the environmental impact of medicines: from water analysis and

Irene Cristini, Elisabetta Poluzzi, Federica Soardo, Salvatore Crisafulli, Stefano Polesello, Ursula Kirchmayer, Marco Milani, Francesca Russo, Michele Nicoletti, Giovanna Scroccaro and 6 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in drug safety and regulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Irene CristiniDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Elisabetta PoluzziDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Federica SoardoDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Salvatore CrisafulliDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Stefano PoleselloNational Research Council, Water Research Institute, CNR-IRSA, Brugherio, Monza and Brianza, Italy.
Ursula KirchmayerDepartment of Epidemiology, Lazio Regional Health Service, Rome, Italy.
Marco MilaniRegional Directorate of Prevention, Food Safety, Veterinary Public Health - Regione del Veneto, Venice, Italy.
Francesca RussoRegional Directorate of Prevention, Food Safety, Veterinary Public Health - Regione del Veneto, Venice, Italy.
Michele NicolettiRegional Directorate of Prevention, Food Safety, Veterinary Public Health - Regione del Veneto, Venice, Italy.
Giovanna ScroccaroRegional Directorate of Pharmaceutical, Prosthetic, Medical Device - Regione del Veneto, Venice, Italy.
Paola DeambrosisRegional Directorate of Pharmaceutical, Prosthetic, Medical Device - Regione del Veneto, Venice, Italy.
Shima Tavakolian HaghighiDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Jacopo GrisottoDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Ugo MorettiDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Giovanna Paolone *Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Gianluca Trifirò *Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The environmental impact of medicines has become a growing concern within the One Health framework, which emphasizes the interconnection of human, animal, and environmental health. This narrative review, based on discussions from a 2025 Italian multistakeholder roundtable, explores current strategies for assessing and reducing such impact, including water monitoring,

Indexed as

environmental pharmacoepidemiologyenvironmental risk assessmentone healthpharmaceutical pollutionsustainable prescribing

Identifiers

PMID41488933
PMCPMC12756347

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.