Evidence map›Paper›PMID 41489360›Full record

ReviewApplied and environmental microbiology2026

Microbial interactions in facilitating antibiotic activity and resistance evolution.

Lujie Zhang, Shenmiao Li, Ziqi Liu, Run-Run Zhang, Tian Yang, Donghong Liu, Tian Ding, Xiaonan Lu, Jinsong Feng

Abstract readReview
In one paragraph

Review in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lujie ZhangCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Shenmiao LiDepartment of Food Science and Agricultural Chemistry, McGill University, Sainte-Anne-de-Bellevue, Québec, Canada.ORCID 0009-0007-4396-663X
Ziqi LiuCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Run-Run ZhangCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Tian YangDepartment of Food Science and Agricultural Chemistry, McGill University, Sainte-Anne-de-Bellevue, Québec, Canada.
Donghong LiuCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Tian DingCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.ORCID 0000-0002-8403-5344
Xiaonan LuDepartment of Food Science and Agricultural Chemistry, McGill University, Sainte-Anne-de-Bellevue, Québec, Canada.ORCID 0000-0003-0254-0345
Jinsong FengCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.ORCID 0009-0005-8006-5772

Funding

Canada Research Chairs CRC-2024-00011National Key Research and Development Program of China 2024YFD2101100National Key Research and Development Program of China 2024YFD2101101Natural Sciences and Engineering Research Council of Canada RGPIN-2025-03996
6 · The paper itself

Abstract

In polymicrobial communities, microorganisms do not exist in isolation but engage in complex and dynamic interactions. Emerging evidence indicates that these microbial interactions can profoundly influence key aspects of antibiotic action, including antibiotic activity and the emergence and dissemination of antibiotic resistance. This mini-review examines the mechanistic pathways through which intra- and inter-specific interactions facilitate both individual and community-level responses to antibiotic treatment. Such interactions can also reshape the selective pressures imposed by antibiotics, thereby altering evolutionary trajectories toward resistance. We emphasize the importance of considering the ecological context of microbial communities as essential for advancing our understanding of antibiotic resistance and for developing more effective and sustainable antibiotic strategies.

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialDrug Resistance, MicrobialMicrobial InteractionsMicrobiotaBiological EvolutionAnti-Bacterial Agentsantibiotic activityantibiotic resistanceecological contextmicrobial interactions

Identifiers

PMID41489360
PMCPMC12838386

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.