Evidence map›Paper›PMID 41489368›Full record

ReviewJournal of virology2026

Pre-assembled complexes and allosteric effects: parallels between eukaryotic phosphorylation cascades and membrane fusion during herpesviral entry.

Gonzalo L Gonzalez-Del Pino, Ekaterina E Heldwein

Abstract readReview
In one paragraph

Review in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gonzalo L Gonzalez-Del PinoDepartment of Molecular Biology and Microbiology and Tufts NIH-IRACDA Program, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-0365-8583
Ekaterina E HeldweinDepartment of Molecular Biology and Microbiology and Tufts NIH-IRACDA Program, Tufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0003-3113-6958

Funding

Tufts IRACDAK12GM133314 · NIGMS · TUFTS UNIVERSITY BOSTON · PI CLAIRE L MOORE, Jamie Lynn Maguire · 2019 to 2026
$8.4M
Structure, antigenicity, and function of HCMV fusogen gBR01AI164698 · NIAID · TUFTS UNIVERSITY BOSTON · PI HELDWEIN, EKATERINA · 2021 to 2025
$3.4M
Capturing HSV entry glycoprotein complexesR21AI190726 · NIAID · TUFTS UNIVERSITY BOSTON · PI Ekaterina Heldwein · 2025 to 2026
$439k
NIAID NIH HHS R01 AI164698NIAID NIH HHS R21 AI190726NIGMS NIH HHS K12 GM133314NIH HHS K12GM133314NIH HHS R01AI164698NIH HHS R21AI190726
6 · The paper itself

Abstract

Unlike most enveloped viruses,

Indexed as

HerpesviridaeMembrane FusionVirus InternalizationAllosteric RegulationAnimalsHumansPhosphorylationSignal TransductionViral Envelope ProteinsViral Envelope ProteinsallostericgBgDgH/gLglycoproteinHerpesviridaeherpesvirusHSV-1MAPKmembrane fusionnectin-1post-activationpostfusionpre-activationprefusionreceptorsignaling cascadesignal transductionviral entry

Identifiers

PMID41489368
PMCPMC12911881

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.