Evidence map›Paper›PMID 41491080›Full record

ArticleScientific reports2026

Large-scale music events can cause subclinical hearing damage.

Nele De Poortere, Wannes Van Ransbeeck, Sarineh Keshishzadeh, Marcel Kok, Hannah Keppler, Ingeborg Dhooge, Sarah Verhulst

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nele De PoortereDepartment of Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium. nele.depoortere@ugent.be.
Wannes Van RansbeeckDepartment of Information Technology-Hearing Technology @ WAVES, Ghent University, Ghent, Belgium.
Sarineh KeshishzadehDepartment of Information Technology-Hearing Technology @ WAVES, Ghent University, Ghent, Belgium.
Marcel KokdBcontrol, Ghent, Belgium.
Hannah KepplerDepartment of Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Ingeborg DhoogeDepartment of Ear, Nose and Throat, Ghent University Hospital, Ghent, Belgium.
Sarah VerhulstDepartment of Information Technology-Hearing Technology @ WAVES, Ghent University, Ghent, Belgium.

Funding

European Research Council 899858HORIZON EUROPE European Innovation Council 101058278
6 · The paper itself

Abstract

The WHO warns that over 1.1 billion young people are at risk of hearing loss due to unsafe listening practices, particularly in recreational settings. While traditional studies have focused on changes in hearing sensitivity, typically assessed through standard audiometry, emerging research reveals that noise exposure can also damage cochlear synapses without affecting outer hair cells (OHCs). This "hidden" damage, known as cochlear synaptopathy (CS), impairs the reliable processing of audible sound in complex listening environments while having little or no effect on the traditional measure of hearing sensitivity such as the audiogram. This study offers a unique longitudinal investigation of the relationship between recreational noise exposure and both audiometric and hidden hearing changes, combining personal dosimetry with standard audiometry and physiological markers including otoacoustic emissions and auditory-evoked potentials (AEPs). Forty-two young adults were monitored before and after large-scale music events, with average sound exposure reaching 100 ± 4 dBA over 10.3 ± 4.8 h. Only one participant showed a clinically significant decline in hearing sensitivity, yet five showed acute reductions in AEP markers of synaptic damage within 24 h post-exposure. Two of these cases persisted for 14 days, despite normal audiometric thresholds. No correlation was found between exposure levels and damage, suggesting that individual susceptibility is important. These findings emphasize the limitations of standard hearing sensitivity measures and highlight the need for early diagnostic tests that can detect subclinical, or hidden damage. They call for protective strategies and revised monitoring practices that account for real-life variability in personal exposure and auditory vulnerability.

Indexed as

Hearing Loss, Noise-InducedMusicNoiseAcoustic StimulationAdolescentAdultAudiometryAuditory ThresholdCochleaEvoked Potentials, AuditoryFemaleHumansMaleOtoacoustic Emissions, SpontaneousYoung AdultDosimetryRecreational noise exposureSub-clinical hearing lossSuprathreshold auditory evoked potentials

Identifiers

PMID41491080
PMCPMC12780260

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.