ArticleBMC veterinary research2026
Behavioural susceptibility to environmental influences in obesity- evidence from a companion animal model.
Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Obesity is often pejoratively viewed as the consequence of poor self-restraint with the influence of genetics on individuals’ drive to eat overlooked. We studied pet dogs (Canis familiaris) as a compelling animal model in which obesity develops spontaneously, subject to similar environmental influences as in their human counterparts and in which artificial selection means dogs within a breed are genetically homogeneous. In electronic health records from 1.1 million dogs, we showed wide variation in the probability of obesity in different breeds, evidence that obesity is highly heritable in this species. Using a validated questionnaire in ~ 15,000 dog/owner dyads we show that food motivation is a key driver of obesity in dogs, and that high food motivation renders affected dogs particularly susceptible to an obesogenic environment. As well as being of veterinary interest, this is of relevance to human obesity as compelling, data-driven evidence of how behavioural susceptibility to environmental risk governs obesity outcome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.