ReviewArchives of microbiology2026
Probiotic-based mycotoxin detoxification in poultry feed: mechanisms, efficacy, challenges, and future directions for sustainable production.
Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Bacillus-derived antimicrobial peptides as alternatives to antibiotics in poultry: mechanisms, applications, and future prospects- a review.Archives of microbiology · 2026Review
- Synbiotic supplementation modulates humoral immunity and cecal microbiota in broiler chickens exposed to subclinical doses of fumonisins and deoxynivalenol.Frontiers in physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycotoxin contamination remains a significant challenge to poultry health and productivity globally. Conventional detoxification methods, such as chemical adsorption and thermal degradation, are often limited by high costs, nutrient losses, and incomplete toxin removal. In contrast, probiotics offer a promising biological alternative for mycotoxin detoxification. This review critically evaluates the role of probiotics, such as Lactobacillus, Bacillus, and Saccharomyces, in mitigating mycotoxin toxicity through mechanisms of adsorption to cell wall polysaccharides and enzymatic degradation. Probiotic strains Lactobacillus casei and Saccharomyces cerevisiae achieve adsorption efficiencies exceeding 90% for aflatoxins B (AFB₁), while Bacillus strains have demonstrated up to 65% reduction in deoxynivalenol levels in vitro. The detoxification efficacy of probiotics is highly strain- and dose-dependent, with reductions in AFB₁ residues ranging from 30 to 60% in poultry tissue during in vivo trials. While adsorption is well established, the in vivo enzymatic degradation mechanisms remain underexplored, with some strains showing up to a 40% reduction in toxin residues through enzymatic biotransformation. Additionally, emerging strategies using microbial consortia and genetically modified probiotics show promising results, with consortia reducing toxin loads by 40-65% in field trials. However, large-scale validation and consistent performance in commercial poultry production remain limited. This review identifies critical research gaps, including strain selection, biofilm regulation, and the need for standardized field-level efficacy trials. Probiotic-based detoxification is positioned as a biologically sustainable complement to, rather than a complete replacement for, conventional chemical methods, offering potential for safer feed and improved poultry health within a broader food safety framework.
Indexed as
Identifiers
41493458What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.