Evidence map›Paper›PMID 41493537›Full record

ArticleSports medicine (Auckland, N.Z.)2026

Correlations Between the Metabolic Costs of Level and Graded Running: A Secondary Analysis of the Literature.

Loïc Espeit, Thibault Besson, Frederic Sabater-Pastor, Jeanne Tondut, Wouter Hoogkamer, Rodger Kram, Marcel Lemire, Grégoire P Millet, Aldo Savoldelli, Fabrice Vercruyssen and 2 more

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Article in Sports medicine (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Loïc EspeitInter-University Laboratory of Human Movement Biology, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.
Thibault BessonInter-University Laboratory of Human Movement Biology, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.
Frederic Sabater-PastorInter-University Laboratory of Human Movement Biology, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.
Jeanne TondutInter-University Laboratory of Human Movement Biology, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.
Wouter HoogkamerDepartment of Kinesiology, University of Massachusetts Amherst, Amherst, MA, USA.
Rodger KramIntegrative Physiology Department, University of Colorado, Boulder, CO, USA.
Marcel LemireFaculty of Sport Sciences, University of Strasbourg, Strasbourg, France.
Grégoire P MilletInstitute of Sport Sciences, University of Lausanne, Lausanne, Switzerland.
Aldo SavoldelliDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Fabrice VercruyssenLaboratory Youth-Physical Activity and Sports-Health (JAP2S), Toulon University, Toulon, France.
Gianluca VernilloCeRiSM (Research Center Sport Mountain and Health), University of Verona and University of Trento, Rovereto, Italy.
Guillaume Y MilletInter-University Laboratory of Human Movement Biology, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France. guillaume.millet@univ-st-etienne.fr.ORCID 0000-0002-6395-0762

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe metabolic cost of running (Cr) is one of the three main determinants of performance in distance running, along with maximum oxygen consumption and lactate threshold. However, level Cr is only weakly correlated with performance in trail running, which almost always involves uphill and downhill sections.

objectiveThrough a secondary analysis of published data, the primary aim of this study was to characterize the correlations between individuals' level and graded (downhill and uphill) Cr. We took advantage of this database to also re-evaluate the pattern and critical points (i.e., optimum slope) of the relationship between Cr and slope.

methodsWe analyzed 23 studies evaluating level and graded Cr, published before August 2024. Both Cr and Pearson correlation coefficients between level and graded Cr were plotted as functions of slope.

resultsUsing third-order polynomial functions, a correlation between level and graded Cr was a continuous function of slope in which correlation coefficients declined with progressively steep uphill or downhill slopes. Downhill Cr was minimized at - 18.8%, and a linear relationship was observed for uphill Cr with slope across the range of slopes analyzed (up to + 26.8%).

conclusionsThe present secondary analysis extends our knowledge on the influence of slope on Cr, showing that graded Cr is weakly correlated with level Cr when slope is steeper than ± 10%. Consequently, testing and training protocols for trail runners should incorporate steeper slopes (i.e., ± 15%) to provide more relevant assessments and preparation for mountainous trail races (including steep slopes).

Indexed as

Athletic PerformanceEnergy MetabolismRunningHumansLactic AcidOxygen ConsumptionLactic Acid

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.