Evidence map›Paper›PMID 41493877›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Relationships between heritable dementia risk factors, cardiovascular risk factors in young adulthood, and midlife neuropsychological outcomes.

Ivan Koychev, Nemanja Vaci, Justine Moonen, Graham Reid, Gregory Howgego, Kristine Yaffe, Ilya Nasrallah, Stephen Sidney, Christoph Jindra, John Gallacher and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ivan KoychevDepartment of Psychiatry, University of Oxford, Oxford, UK.
Nemanja VaciDepartment of Psychology, University of Sheffield, Sheffield, UK.ORCID 0000-0002-8094-0902
Justine MoonenIntramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Graham ReidDepartment of Experimental Psychology, University of Oxford, Oxford, UK.ORCID 0000-0002-6079-9323
Gregory HowgegoDepartment of Psychiatry, University of Oxford, Oxford, UK.
Kristine YaffeDepartments of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Ilya NasrallahHospital of the University of Pennsylvania, Philadelphia, PA, USA.
Stephen SidneyDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Christoph JindraDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0002-9388-0443
John GallacherDepartment of Psychiatry, University of Oxford, Oxford, UK.
Lenore J LaunerIntramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

Funding

Hypertension, Blood Pressure Targets, and Alzheimer’s Disease and Dementia Risk and Disparities among Nationally Representative US VeteransR01AG085481 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2025 to 2025
$793k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INIA NIH HHS R01 AG085481
6 · The paper itself

Abstract

BackgroundSelected cardiovascular factors,

Indexed as

Cardiovascular DiseasesDementiaHeart Disease Risk FactorsAdolescentAdultApolipoprotein E4BrainCognitionFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsRisk FactorsApolipoprotein E4Alzheimer's diseaseAPOE4 carriershipdementiadyslipidemiamodifiable risk factors

Identifiers

PMID41493877
PMCPMC12775168

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.