Evidence mapPaperPMID 41494239Full record

ReviewEBioMedicine2026

Nanotechnology for atherosclerotic plaque stabilisation: bridging innovation and clinical practice.

Yuxin Ren, Yujia Zhou, Boyang Xiang, Qingguo Li, Xiang Zhou

Abstract readReview
In one paragraph

Review in EBioMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuxin RenDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yujia ZhouDepartment of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Boyang XiangDepartment of Cardiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qingguo LiDepartment of Cardiovascular Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiang ZhouDepartment of Cardiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China. Electronic address: zhouxiang@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulnerable plaques, also known as high-risk plaques, are the main cause of acute cardiovascular events. Advances in nanotechnology have made it possible to monitor and stabilise these plaques. This review outlines the pathophysiological basis of vulnerable atherosclerotic plaques and explores the emerging role of nanoplatforms in their diagnosis and treatment. By integrating recent research advances, we highlight key strategies for plaque stabilisation from a clinical perspective and present a comprehensive framework to connect mechanistic insights with translational applications. In addition, we consider the major unresolved challenges in the field and suggest possible future directions. This review aims to facilitate the clinical translation of nanotechnology-based approaches and help bridge the gap between preclinical research and real-world clinical practice.

Indexed as

NanotechnologyPlaque, AtheroscleroticAnimalsAtherosclerosisHumansNanomedicineAtherosclerosisNanotechnologyVulnerable plaques

Identifiers

PMID41494239
PMCPMC12809741

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.