Evidence map›Paper›PMID 41495053›Full record

ReviewNPJ biofilms and microbiomes2026

Unraveling the microbial landscape in prostate cancer: pathogenesis to therapy.

Xiancai Du, Jing Wu, Siyuan Xia, Hao Zheng, Baotong Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ biofilms and microbiomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiancai DuDepartment of Human Cell Biology and Genetics, School of Medicine and SUSTech Homeostatic Medicine Institute (SHMI), Southern University of Science and Technology, Shenzhen, Guangdong, China.
Jing WuDepartment of Human Cell Biology and Genetics, School of Medicine and SUSTech Homeostatic Medicine Institute (SHMI), Southern University of Science and Technology, Shenzhen, Guangdong, China.
Siyuan XiaDepartment of Human Cell Biology and Genetics, School of Medicine and SUSTech Homeostatic Medicine Institute (SHMI), Southern University of Science and Technology, Shenzhen, Guangdong, China. xiasy@sustech.edu.cn.
Hao ZhengCollege of Food Science and Nutritional Engineering, China Agricultural University, Beijing, China. hao.zheng@cau.edu.cn.
Baotong ZhangDepartment of Human Cell Biology and Genetics, School of Medicine and SUSTech Homeostatic Medicine Institute (SHMI), Southern University of Science and Technology, Shenzhen, Guangdong, China. zhangbt@sustech.edu.cn.

Funding

Department of Science and Technology of Guangdong Province 2021QN02Y875Guangdong Basic and Applied Basic Research Foundation 2024B1515020020National Natural Science Foundation of China 82273260 and 82472877National Natural Science Foundation of China 82473084 and 82273079Science, Technology and Innovation Commission of Shenzhen Municipality JCYJ20240813094923032Technology and Innovation Commission of Shenzhen Municipality 20220814161004001 and RCYX20231211090317011
6 · The paper itself

Abstract

Emerging evidence suggests a role of microbiota in prostate cancer, yet this association remains poorly understood. This review systematically examines microbes from the skin, oral cavity, gut, urinary tract, and the prostate cancer microenvironment, summarizing how these communities affect prostate cancer initiation, progression, and therapeutic response. We highlight key molecular pathways and metabolic reprogramming events underlying host-microbiota interactions and outline current findings and knowledge gaps to guide microorganism-based therapeutic strategies.

Indexed as

MicrobiotaProstatic NeoplasmsBacteriaHost Microbial InteractionsHumansMaleMouthSkinTumor MicroenvironmentUrinary Tract

Identifiers

PMID41495053
PMCPMC12868656

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.