Observational studyScientific reports2026
Role of frailty in otorhinolaryngology and head and neck surgery in a secondary and a tertiary care center: a prospective observational two-cohort study.
Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
The proportion of elderly patients undergoing otolaryngology and head and neck surgery (OLHNS) is continuously increasing. The present prospective study evaluated whether frailty in patients ≥ 65 years of age was an important predictor of perioperative complications. An unselected series of 276 elderly patients (67% male; median age: 74 years; Charlson Comorbidity Index (CCI) 2+: 85%) undergoing OLHNS surgery in a 6-month period in 2022 and 2023, respectively, in a secondary and in a tertiary care hospital completed the Groningen Frailty Indicator questionnaire. Primary outcome measure was postoperative complications measured with the Clavien-Dindo classification (CDC), which were analyzed using univariate and multivariate binary logic regression models. 34.7% of the patients were frail. Female gender (Odds ratio [OR] = 2.158; confidence interval [CI] = 1.229 to 3.791; p = 0.007) and the CCI (OR = 1.258; CI = 1.135 to 1.396; p < 0.001) were independent predictors for frailty. 22.8% had CDC complications. Frailty (OR = 1.805; CI = 1.001 to 3.252; p = 0.049) and a CCI 2+ (OR = 4.821; CI = 1.102 to 21.079; p = 0.037) were independent predictors for postoperative CDC complications. The inclusion of a frailty assessment into the pre-operative risk assessment is recommended for all patients ≥ 65 years of age planned for OLHNS.
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