ReviewCurrent opinion in clinical nutrition and metabolic care2026
Skeletal muscle protein turnover and mitochondrial responses to omega-3 fatty acid supplementation: an update.
Review in Current opinion in clinical nutrition and metabolic care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Preventive Strategies to Reduce Sarcopenia Risk During GLP-1-Based Anti-Obesity Therapy.Journal of clinical medicine · 2026Review
- Association between triglyceride-glucose index and sarcopenia in older adults without either dysglycemia or central obesity: a cross-sectional study from CHARLS.Open medicine (Warsaw, Poland) · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
purpose of reviewTo critically review recent findings related to the effects of omega-3 fatty acid supplementation on skeletal muscle, with a particular focus on skeletal muscle protein turnover and mitochondrial function. RECENT
findingsEvidence indicates that omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may support skeletal muscle health by influencing muscle protein synthesis (MPS), mitochondrial function, and redox balance. However, recent meta-analyses reveal inconsistent effects of omega-3 fatty acid supplementation on basal and stimulus-induced MPS, likely due to methodological variability. Omega-3 fatty acid supplementation is seemingly more beneficial in clinical cohorts and preclinical data suggests omega-3s may reduce oxidative stress. SUMMARY: Omega-3 fatty acid supplementation is a promising nutritional strategy for supporting skeletal muscle health, via the modulation of MPS and mitochondrial function. However, large-scale trials in a variety of healthy and clinical populations using sustainable sources of omega-3 fatty acids are required before a consensus on efficacy can be made.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.