Evidence map›Paper›PMID 41496962›Full record

ArticleAnnals of medicine and surgery (2012)2026

Circulating microRNAs in post myocardial infarction remodeling: toward precision cardiology.

Muhammad Khizar, Muhammad Zaib, Muhammad Bilal, Hasibullah Aminpoor, Hasiba Karimi

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad KhizarFaculty of Medicine, Georgian American University Manifest Medical Research Co, Tbilisi, Georgia.ORCID https://orcid.org/0009-0005-5229-5052
Muhammad ZaibFaculty of Medicine, Georgian American University Manifest Medical Research Co, Tbilisi, Georgia.ORCID https://orcid.org/0009-0008-7675-7161
Muhammad BilalFaculty of Medicine, Shahida Islam Medical and Dental College, Lodhran, Punjab, Pakistan.ORCID https://orcid.org/0009-0007-5130-509X
Hasibullah AminpoorFaculty of Medicine, Kabul University of Medical Sciences "Abu Ali Ibn Sina", Kabul, Afghanistan.ORCID https://orcid.org/0000-0003-1817-7800
Hasiba KarimiFaculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-7618-3849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-myocardial infarction (MI) ventricular remodeling is a major cause of heart failure, despite advances in revascularization and pharmacotherapy. Circulating microRNAs (miRNAs) are emerging as biomarkers for risk stratification and therapeutic targeting. This letter reviews their role in apoptosis, inflammation, and fibrosis, highlights studies from Europe, Asia, and North America, and discusses technological advances, including exosome-based miRNA panels and machine learning models. Limitations include analytical variability, limited geographic representation, and lack of integration into clinical care. Recommendations include standardizing methods, conducting large international studies, and developing actionable miRNA algorithms. Integrating miRNA profiling into post-MI care has the potential to improve risk assessment, personalize therapy, and reduce the burden of heart failure.

Indexed as

biomarkerscirculating microRNAsfibrosismyocardial infarctionprecision cardiologyventricular remodeling

Identifiers

PMID41496962
PMCPMC12767986

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.