ArticleJournal of veterinary research2025
Investigation of an association between
Article in Journal of veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Introduction: Small ruminant lentivirus (SRLV) infections occur worldwide in goats and sheep and have negative impact on the production and welfare of animals. During recent years, many studies have focused on the host factors that determine the resistance of individual animals to SRLV infection; consideration of such factors would be an alternative to current control programmes based on culling seropositive animals. The aim of this study was to analyse the relationship between the expression of two previously selected goat genes, Material and Methods: Primary fibroblast cultures obtained from the skin of goats with high SRLV proviral DNA load (HPL), low proviral load (LPL) or free of infection were inoculated with the A5 SRLV subtype circulating in the flock. The course of infection was observed based on cytopathic changes in cell cultures and the presence of SRLV A5 RNA, of which the level was monitored using a quantitative reverse-transcription PCR. The relative expression of the selected host genes following SRLV infection was analysed. Results: The kinetics of SRLV replication differed, and distinctly higher numbers of SRLV particles were detected in cells derived from the HPL animal. The expression profiles of Conclusion: The observed relationship between expression of
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