Evidence map›Paper›PMID 41498040›Full record

ArticleMediators of inflammation2025

Rongbei Maimendong Decoction Promotes Radiosensitivity of Non-Small Cell Lung Cancer Cells by Inhibiting SOD1 Expression.

Shilong Liu, Xueying Pang, Liqun Wang, Ning Zhan, Shangjie Wu, Jiaxing Deng, Ke Jin, Yang Bai, Deyou Jiang, Lishuang Qi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shilong LiuDepartment of Respiratory, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.ORCID https://orcid.org/0009-0001-6868-2752
Xueying PangDepartment of Oncology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.ORCID https://orcid.org/0009-0003-1806-7684
Liqun WangDepartment of Thoracic Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, China, hrbmu.edu.cn.
Ning ZhanDepartment of Radiation Oncology, Xiang'an Hospital of Xiamen University, Xiamen, China, xmu.edu.cn.
Shangjie WuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China, hrbmu.edu.cn.
Jiaxing DengCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China, hrbmu.edu.cn.
Ke JinDepartment of Thoracic Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, China, hrbmu.edu.cn.
Yang BaiDepartment of Thoracic Radiation Oncology, Harbin Medical University Cancer Hospital, Harbin, China, hrbmu.edu.cn.
Deyou JiangCollege of Basic Medical Science, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.
Lishuang QiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China, hrbmu.edu.cn.ORCID https://orcid.org/0000-0002-2991-6544
Zhuying LiDepartment of Respiratory, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, China, hljucm.edu.cn.ORCID https://orcid.org/0009-0006-9282-2619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some natural remedies in traditional Chinese medicine (TCM) inhibit tumor progression and increase sensitivity in the treatment of patients who have received radiation therapy. However, the specific synergistic effect of the active ingredients in the traditional Chinese therapeutic Rongbei Maimendong decoction (RBMD) on sensitivity to radiation therapy for non-cell lung cancer (NSCLC) is still unclear. RBMD inhibited transplanted tumor cell growth in mice, showing a dose-dependent effect in tumor growth inhibition following radiotherapy. Our study utilized bioinformatics analysis and liquid chromatography with tandem mass spectrometry to identify the presence of β-thymidine (β-thy) in

Indexed as

Carcinoma, Non-Small-Cell LungDrugs, Chinese HerbalLung NeoplasmsRadiation ToleranceSuperoxide Dismutase-1AnimalsApoptosisCell Line, TumorCell ProliferationHumansMiceMice, NudeDrugs, Chinese HerbalSuperoxide Dismutase-1NSCLCradiosensitivityRongbei Maimendong decoction (RBMD)SOD1β-thymidine

Identifiers

PMID41498040
PMCPMC12767424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.