ArticleeLife2026
Identification of a
Kyle Spinler, Michael Hamilton, Jeevisha Bajaj, Yutaka Shima, Emily Diaz, Marcie Kritzik, Tannishtha Reya
Abstract read
In one paragraphArticle in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors.
Kyle SpinlerDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Michael HamiltonDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Jeevisha BajajDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Yutaka ShimaDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Emily DiazDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Marcie KritzikDepartments of Pharmacology and Medicine, University of California San Diego School of Medicine La Jolla, San Diego, United States.
Funding
GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5MContemporary Approaches to Cancer Cell Signaling and CommunicationT32CA009523 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DONOGHUE, DANIEL J, YANG, JING · 1985 to 2025
$12.1MMolecular strategies for early detection and targeting of cancerR35CA197699 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Tannishtha Reya · 2015 to 2026
$11.2MU of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0MBlood Cells in Hemostasis and ThrombosisT32HL086344 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GINSBERG, MARK HOWARD · 2008 to 2023
$4.4MNCI NIH HHS R35 CA197699NCI NIH HHS T32 CA009523NHLBI NIH HHS T32 HL086344NIGMS NIH HHS T32 GM007752NIH HHS R35 CA197699NIH HHS T32 CA009523NIH HHS T32 GM007752NIH HHS T32 HL086344NINDS NIH HHS P30 NS047101
6 · The paper itselfAbstract
Myeloid leukemias, diseases marked by aggressiveness and poor outcomes, are frequently triggered by oncogenic translocations. In the case of chronic myelogenous leukemia (CML), the BCR-ABL fusion initiates chronic phase disease with second hits allowing progression to blast crisis. Although Gleevec has been transformative for CML, blast crisis CML remains relatively drug resistant. Here, we show that
Indexed as
OncogenesRNA-Binding ProteinsTranslocation, GeneticAnimalsFusion Proteins, bcr-ablHomeodomain ProteinsHumansMiceFusion Proteins, bcr-ablhomeobox protein HOXA9Homeodomain ProteinsMSI2 protein, humanRNA-Binding ProteinsbcCMLcancer biologymouseMSI2-HOXA9 translocationMusashi2myeloid leukemiaoncogene
Identifiers
PMID41498402
PMCPMC12779265
What Socratic holds
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LicenceCC BY
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