ReviewParasite immunology2026
The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review.
Review in Parasite immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Omics landscapes of hepatic echinococcosis: bulk foundations, emerging single-cell studies, and analytical considerations.Frontiers in immunology · 2026Review
- The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review.Parasite immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Hepatic echinococcosis (HE), a major zoonotic disease, remains endemic in pastoral regions of Western China, where its incidence is closely linked to geographical, livestock and sanitary conditions. The disease presents a significant clinical challenge due to the complexity of host-parasite interactions and a high recurrence rate. To date, the underlying pathogenesis and effective prevention and control strategies remain inadequately studied. Particularly, it is still unclear how innate lymphoid cells (ILCs) affect disease progression and therapeutic intervention. This review focuses on ILCs and their emerging role in the pathogenesis of HE. Through an in-depth analysis of the biological characteristics of ILCs, we revealed their significant role in immune responses and therapeutic mechanisms. Additionally, we also investigated their dynamic involvement in the development of HE. Furthermore, the specific role of gene editing in modulating ILC function was examined. Clinically, we assessed the distribution and functional status of ILCs in patients with HE and analysed their association with hepatic fibrosis and other complications. Finally, we explored novel diagnostic and therapeutic strategies based on ILC functional modulation. In short, this review highlights the critical role of ILCs in shaping the immunological landscape of HE, offering a theoretical basis for the development of ILC-targeted diagnosis and treatment of the disease. Through ILC functional modulation, the intervention of fibrotic progression and immune imbalance holds promise for overcoming current therapeutic limitations and advancing clinical translation.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.