Evidence map›Paper›PMID 41498563›Full record

ReviewLab on a chip2026

Microfluidics for cell therapy and manufacturing in oncology and regenerative medicine.

Josie L Duncan, Julio P Arroyo, Rafael V Davalos

Abstract readReview
In one paragraph

Review in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Josie L DuncanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology-Emory University, Atlanta, GA, USA. rafael.davalos@bme.gatech.edu.ORCID 0000-0002-4743-1540
Julio P ArroyoWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology-Emory University, Atlanta, GA, USA. rafael.davalos@bme.gatech.edu.ORCID 0000-0003-4690-6337
Rafael V DavalosWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology-Emory University, Atlanta, GA, USA. rafael.davalos@bme.gatech.edu.ORCID 0000-0003-1503-9509

Funding

ADDITIVE MANUFACTURING OF PDMS MICROFLUIDICSR44TR003968 · NCATS · PHASE, INC. · PI SCHULTZ, JEFFREY · 2023 to 2024
$2.0M
NCATS NIH HHS R44 TR003968
6 · The paper itself

Abstract

Microfluidics has offered invaluable insight into diagnostics and point-of-care applications due to its small footprint, low costs, and minimal power requirements. As cellular manufacturing has shown significant promise for treating previously insurmountable diseases, microfluidics has expanded its reach into immunotherapy and regenerative medicine with a clinical perspective. Conventional methods to reprogram a target cell to improve prognosis, while innovative on their own, face challenges that miniaturized systems are poised to address. Here, we provide an overview of microfluidic-based technology that highlights significant strides within the field of cell manufacturing to treat cancer and degenerative diseases. We highlight commonly used mechanisms to isolate, transfect, and expand target cells in microfluidic devices. We discuss specific innovative microfluidic-based approaches that demonstrate comparable or exceptional performance compared to traditional methods.

Indexed as

Cell- and Tissue-Based TherapyLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesNeoplasmsRegenerative MedicineAnimalsHumans

Identifiers

PMID41498563
PMCPMC12777651

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.