Evidence map›Paper›PMID 41498655›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation.

Ang Dong, Yihan Meng, Stephen Shing-Toung Yau, Shing-Tung Yau, Rongling Wu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ang DongBeijing Key Laboratory of Topological Statistics and Applications for Complex Systems, Beijing Institute of Mathematical Sciences and Applications, Beijing, China.
Yihan MengBeijing Key Laboratory of Topological Statistics and Applications for Complex Systems, Beijing Institute of Mathematical Sciences and Applications, Beijing, China.
Stephen Shing-Toung YauBeijing Key Laboratory of Topological Statistics and Applications for Complex Systems, Beijing Institute of Mathematical Sciences and Applications, Beijing, China.
Shing-Tung YauBeijing Key Laboratory of Topological Statistics and Applications for Complex Systems, Beijing Institute of Mathematical Sciences and Applications, Beijing, China.
Rongling WuBeijing Key Laboratory of Topological Statistics and Applications for Complex Systems, Beijing Institute of Mathematical Sciences and Applications, Beijing, China.ORCID https://orcid.org/0009-0000-0005-1025

Funding

Interdisciplinary Project at Shanghai Institute for Mathematics and Interdisciplinary Sciences SIMIS-ID-2024-WN
6 · The paper itself

Abstract

Grafting has been practiced for millennia to combine the best characteristics of two plants. Despite recent molecular discoveries that gain insight into plant grafting, the systematic characterization of its underlying mechanisms is still lacking. Here, we take a step toward filling this gap by developing a generalized statistical mechanics model to decode genomic crosstalk between the scion and rootstock. Instead of traditional objectives of identifying individual genes that are differentially expressed between the two organs, our model codes thousands of interactive genes into informative, dynamic, omnidirectional, and personalized networks (idopNetworks) that program and rewire scion-rootstock crosstalk. We design an experiment of reciprocally micrografting young tissues to validate the application of idopNetworks to the genomic characterization of graft formation between two distantly related Populus species. Given its capacity to reveal the most comprehensive genomic underpinnings for proper interactions of the scion with rootstock to develop new plants, the idopNetworks model can be extended for the mechanistic exploration of a wide range of biological, evolutionary, and medical phenomena.

Indexed as

Gene Regulatory NetworksModels, StatisticalPlant RootsPopulusGene Expression Regulation, Plantgene regulatory network modelinggraft incompatibilityplant graftingtissue crosstalkvascular reconnection

Identifiers

PMID41498655
PMCPMC12915093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.