Evidence mapPaperPMID 41500620Full record

ArticleBMJ open2026

24-hour movement behaviours and cardiometabolic health in adults with type 2 diabetes: a comparative cross-sectional and longitudinal analysis.

Lotte Bogaert, Marieke De Craemer, Eveline Dirinck, Patrick Calders, Bruno Lapauw, Iris Willems

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04993482 (24-hour Movement Behaviors Among Type 2 Diabetes Mellitus Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04993482 recruitingnot on this map

24-hour Movement Behaviors Among Type 2 Diabetes Mellitus Patients

TypeobservationalSponsorUniversity Hospital, GhentRan2021 to 2026Enrolled248ConditionsDiabetes Mellitus, Type 2ArmsNo intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lotte BogaertDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium.
Marieke De CraemerDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium marieke.decraemer@ugent.be.ORCID http://orcid.org/0000-0002-5220-7850
Eveline DirinckDepartment of Endocrinology, University of Antwerp, Antwerp, Belgium.
Patrick CaldersDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0001-6327-8155
Bruno LapauwDepartment of Endocrinology, Ghent University Hospital, Ghent, Belgium.
Iris WillemsDepartment of Rehabilitation Sciences, Ghent University, Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMeeting the recommended guidelines for physical activity (PA), sedentary behaviour (SB) and sleep, collectively referred to as 24-hour movement behaviours (24h-MBs), is crucial for type 2 diabetes mellitus (T2DM) management and is associated with favourable health outcomes. However, it is suggested that adults with T2DM spend more time in SB and less time in PA compared with adults without diabetes.

objectivesThis study aims to compare 24h-MBs between adults with and without T2DM (ie, controls with similar characteristics except for having T2DM), investigate how this is associated with cardiometabolic health, and assess changes in 24h-MBs after two years of follow-up (FU) in adults with T2DM.

designCross-sectional and longitudinal study.

settingCommunity-dwelling adults with T2DM and controls in Belgium. PRIMARY OUTCOME MEASURES: This study took place between September 2021 and December 2023. The 24h-MBs were measured using accelerometers (Actigraph wGT3X+); cardiometabolic variables (adiposity, blood pressure and advanced glycation end-products) were collected in both groups. In adults with T2DM, fasting blood samples were collected at baseline and second FU. Compositional data analysis was used to explore group differences in 24h-MBs using multivariate analysis of variance, and regression models analysed associations with cardiometabolic health. Changes in 24h-MBs over time in adults with T2DM were assessed using a linear mixed model.

results52 adults with T2DM (mean age 63.2 SD 10.6) and 74 controls (mean age 62.7 SD 9.4) were included in the cross-sectional analysis. The 24h-MBs of adults with T2DM differed significantly from the controls (p=0.026). Adults with T2DM spent significantly less time in light (-34.7 min/day) and moderate to vigorous PA (MVPA) (-24.1 min/day) compared with controls. In adults with T2DM, reallocating 30 min from any behaviour to MVPA was associated with a significant increase in high-density lipoprotein-cholesterol (sleep: 5.05 mg/dL (2.45; 7.80), standardised effect size (ES)=0.53; SB: 4.53 mg/dL (1.93; 7.27), ES=0.47; light PA: 5.29 mg/dL (2.07; 8.73), ES=0.55) whereas in the control group significant decreases in waist circumference were found when reallocating 30 min from SB to sleep (2.42 cm (0.86-3.97), ES=0.34). 37 (mean age 65.0 SD 9.5) and 22 (mean age 67.0 SD 7.7) adults with T2DM provided valid data after 1 year and 2 years of FU, respectively. No significant changes in 24h-MBs were found after 1-year (p=0.93) or 2-year (p=0.79) FU among adults with T2DM.

conclusionAdults with T2DM have a less favourable 24h-MB composition compared to adults without T2DM, indicating the need for additional effort to achieve and maintain the guidelines. Despite the limited associations found, time reallocations from other behaviours to MVPA theoretically suggest the biggest health benefits.

trial registrationNCT04993482.

Indexed as

Diabetes Mellitus, Type 2ExerciseSedentary BehaviorAccelerometryAdultAgedBelgiumBlood PressureCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSleepCardiovascular DiseaseDiabetes Mellitus, Type 2Physical Fitness

Identifiers

PMID41500620
PMCPMC12778214

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.