Evidence map›Paper›PMID 41500936›Full record

ReviewACS infectious diseases2026

Infectious Diarrhea in Early Childhood across the Global South: Etiologic Diversity and Pathogenic Mechanisms.

Dharitri Chaudhuri, Dipro Mukherjee, Avinash R Shenoy, Sandhya S Visweswariah

Abstract readReview
In one paragraph

Review in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dharitri ChaudhuriDepartment of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru 560012, India.
Dipro MukherjeeDepartment of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru 560012, India.
Avinash R ShenoyDepartment of Infectious Disease, Imperial College London, London SW7 2AZ, UK.
Sandhya S VisweswariahDepartment of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru 560012, India.ORCID 0000-0003-2786-7344

Funding

Mechanisms underlying diarrhea and gut inflammation mediated by Enterotoxigenic and Enteropathogenic E. coliR01AI169618 · NIAID · INDIAN INSTITUTE OF SCIENCE · PI Sandhya Visweswariah · 2023 to 2026
$482k
DBT-Wellcome Trust India Alliance IA/TSG/21/1/60025NIAID NIH HHS R01 AI169618
6 · The paper itself

Abstract

Globally, diarrhea is the third leading cause of death in children below the age of five and is an acute problem in low- and middle-income countries (LMICs), where there is inadequate hygiene, poor sanitation, and a lack of access to clean drinking water. Infectious agents, such as bacteria, viruses, and protozoa, are primarily responsible for causing diarrhea. Despite significant progress in research over the past few decades, there are no licensed vaccines for most of these pathogens. Further, the growing problem of antimicrobial resistance has complicated treatment options. In this review, we provide an overview of the distinct yet often overlapping pathogenesis mechanisms employed by the diverse enteropathogens prevalent in the Global South. Future research should aim to exploit these mechanisms for the design of effective therapeutics and vaccines.

Indexed as

DiarrheaDeveloping CountriesHumansdiarrheal diseaseenteropathogensgut infectionlow- and middle-income countries (LMICs)mucustherapeuticsvaccines

Identifiers

PMID41500936
PMCPMC13196422

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.