Evidence mapPaperPMID 41501143Full record

ArticleScientific reports2026

Prognostic value of the ratio of globally sclerotic glomeruli in patients with idiopathic IgA nephropathy.

Sinan Kazan, Savaş Öztürk, Müge Uzerk Kibar, Seyda Gul Ozcan, Raife Dilhan Alcelik Karacan, Necmi Eren, Mahmut Gok, Kultigin Turkmen, Hamad Dheir, Taner Basturk and 35 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Sinan KazanDepartment of Nephrology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey. sinankazan@hotmail.com.
Savaş ÖztürkDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Müge Uzerk KibarClinic of Nephrology, Ankara Bilkent City Hospital, Ankara, Turkey.
Seyda Gul OzcanDivision of Nephrology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Raife Dilhan Alcelik KaracanDivision of Nephrology, Department of Internal Medicine, Haseki Training and Research Hospital, Istanbul, Turkey.
Necmi ErenDepartment of Nephrology, Faculty of Medicine, Kocaeli University, İzmit, Turkey.
Mahmut GokDepartment of Nephrology, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Kultigin TurkmenDepartment of Nephrology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
Hamad DheirDepartment of Nephrology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Taner BasturkDepartment of Nephrology, Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Erhan TatarMedical Point Hospital, Clinic of Nephrology, Izmir Economy University, İzmir, Turkey.
Omer Faruk AkcayDepartment of Nephrology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Meltem GürsuDepartment of Nephrology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Hakki ArikanDepartment of Nephrology, School of Medicine, Marmara University, Istanbul, Turkey.
Sena UluDepartment of Nephrology, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Mehmet Deniz AyliDepartment of Nephrology, Etlik City Hospital, University of Health Sciences, Ankara, Turkey.
Ilhan KurultakDepartment of Nephrology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Dilek Guven TaymezClinic of Nephrology, Kocaeli State Hospital, İzmit, Turkey.
Belda DursunDepartment of Nephrology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
Ramazan OzturkDepartment of Nephrology, Ankara Training and Research Hospital, Ankara, Turkey.
Sim KutlayDepartment of Nephrology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Sebnem KarakanDepartment of Nephrology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, Turkey.
Murvet YilmazDepartment of Nephrology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Dilek TorunDepartment of Nephrology, Faculty of Medicine, Dr. Turgut Noyan Medical and Research Center, Baskent University, Adana, Turkey.
Kenan TurgutalpDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Mersin University, Mersin, Turkey.
Alper AzakDepartment of Nephrology, Balikesir Ataturk Education and Research City Hospital, University of Health Sciences, Balikesir, Turkey.
Zeki AydinDepartment of Nephrology, Darica Farabi Training and Research Hospital, University of Health Sciences, İzmit, Turkey.
Deren OygarDivision of Nephrology, Dr. Burhan Nalbantoglu State Hospital, Lefkosa, Cyprus.
Nedim Selcuk YilmazDepartment of Nephrology, Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
Bulent KayaDepartment of Nephrology, Faculty of Medicine, Cukurova University, Adana, Turkey.
Zülfükar YilmazDepartment of Nephrology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Ozcan UzunMedical Point Hospital, Clinic of Nephrology, Izmir Economy University, İzmir, Turkey.
Murat Hayri SipahioğluDepartment of Nephrology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Melike Betül ÖğütmenDepartment of Nephrology, Haydarpasa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Serap YadigarClinic of Nephrology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.
Aysegul OrucDepartment of Nephrology, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey.
Mahmud IslamDepartment of Nephrology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Müge DoksanDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Meryem KelesClinic of Nephrology, Ankara Bilkent City Hospital, Ankara, Turkey.
Mehmet Riza AltiparmakDivision of Nephrology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Abdulkadir CelikDivision of Nephrology, Department of Internal Medicine, Haseki Training and Research Hospital, Istanbul, Turkey.
Erkan DervişoğluDepartment of Nephrology, Faculty of Medicine, Kocaeli University, İzmit, Turkey.
Rabia HacerDepartment of Nephrology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Ezgi Coskun YenigunClinic of Nephrology, Ankara Bilkent City Hospital, Ankara, Turkey.
Onur TuncaDepartment of Nephrology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. We assessed whether the Ratio of Globally Sclerotic Glomeruli (RoGSG) on diagnostic biopsy predicts subsequent kidney outcomes in a nationwide, multi‑center registry. Among 326 adults with idiopathic IgAN (mean age 39.1 ± 12.8 years; 60.1% male), 43 patients (13.2%) met a 5 year composite outcome defined as any of: doubling of serum creatinine or ≥ 50% decline in eGFR from baseline, eGFR < 15 mL/min/1.73 m

Indexed as

Glomerulonephritis, IGAKidney GlomerulusAdultBiopsyFemaleGlomerular Filtration RateHumansMaleMiddle AgedPrognosisROC CurveSclerosisGlomerulosclerosisIgA nephropathyKidney outcomePrognostic index

Identifiers

PMID41501143
PMCPMC12830591

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.