Evidence mapPaperPMID 41501360Full record

ArticleScientific reports2026

Increased axial resolution OCT improves structure-function correlation of the disorganization of the retinal inner layers in diabetic retinal disease.

Katharina Wall, Lilith P Arend, Leon von der Emde, Anna Sophia Jauch, Frank G Holz, Marlene Saßmannshausen, Thomas Ach

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Katharina WallDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Lilith P ArendDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Leon von der EmdeDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Anna Sophia JauchDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Frank G HolzDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Marlene SaßmannshausenDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Thomas AchDepartment of Ophthalmology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. thomas.ach@ukbonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine whether optical coherence tomography (OCT) with enhanced axial resolution improves structural characterization of the disorganization of the retinal inner layers (DRIL) in diabetic retinal disease (DRD) and its association with functional and vascular alterations. In this prospective cross-sectional study, 55 diabetic patients, 27 with DRIL (age: 57.1 ± 14.6 years) and 28 eyes without DRIL with diabetes mellitus (DM) type I/II (age: 58.2 ± 13.0 years), were examined with conventional spectral-domain OCT (SD-OCT), High-Resolution (High-Res) OCT, OCT angiography (OCTA), and microperimetry. DRIL areas were significantly smaller on High-Res OCT compared to SD-OCT (mean ± standard deviation, 0.3 ± 0.3 vs. 1.3 ± 1.2 mm

Indexed as

Diabetic RetinopathyRetinaTomography, Optical CoherenceAdultAgedCross-Sectional StudiesFemaleFluorescein AngiographyHumansMaleMiddle AgedProspective StudiesRetinal VesselsDiabetic retinal diseaseDRILOCT, disorganization of the retinal inner layersOptical coherence tomographyStructure-function correlation

Identifiers

PMID41501360
PMCPMC12783662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.