Evidence map›Paper›PMID 41501454›Full record

ArticleNature2026

Albumin orchestrates a natural host defence mechanism against mucormycosis.

Antonis Pikoulas, Ioannis Morianos, Vassilis Nidris, Rania Hamdy, Evangelia Intze, Ángeles López-López, Maria Moran-Garrido, Valliappan Muthu, Maria Halabalaki, Varvara Papaioanou and 31 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Innovation in antifungal therapy.EMBO molecular medicine · 2026
    Review
  3. Review
  4. OesophagealMedical mycology case reports · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

41 authors.

Antonis Pikoulas *School of Medicine, University of Crete, Voutes, Heraklion, Greece.
Ioannis Morianos *School of Medicine, University of Crete, Voutes, Heraklion, Greece.ORCID 0000-0001-5207-0869
Vassilis Nidris *School of Medicine, University of Crete, Voutes, Heraklion, Greece.ORCID 0009-0000-9266-2586
Rania HamdyResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Evangelia IntzeSchool of Medicine, University of Crete, Voutes, Heraklion, Greece.
Ángeles López-LópezCentro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Madrid, Spain.ORCID 0000-0003-1006-4369
Maria Moran-GarridoCentro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Madrid, Spain.
Valliappan MuthuDepartment of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Maria HalabalakiDepartment of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Varvara PapaioanouDepartment of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Maria PapadovasilakiInstitute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece.
Irene KyrmiziSchool of Medicine, University of Crete, Voutes, Heraklion, Greece.ORCID 0000-0002-4284-5816
Yiyou GuDivision of Infectious Diseases, The Lundquist Institute for Biomedical Innovation, Harbor-University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA.
Sandra M Camunas-AlbercaCentro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Madrid, Spain.ORCID 0000-0002-7423-0314
Robina AertsDepartment of Hematology, University Hospitals Leuven, Leuven, Belgium.
Toine MercierDepartment of Hematology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-1517-6426
Yuri VanbiervlietDepartment of Hematology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-6169-1920
Sung-Yeon ChoDepartment of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Amy SpalloneDepartment of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ying JiangDepartment of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dimitrios SamonakisSchool of Medicine, University of Crete, Voutes, Heraklion, Greece.ORCID 0000-0003-0418-4620
Efstathios KastritisSchool of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Carlos LaxDepartamento de Genética y Microbiología, Facultad de Biología, Universidad de Murcia, Murcia, Spain.ORCID 0000-0002-2059-303X
Maria TzardiSchool of Medicine, University of Crete, Voutes, Heraklion, Greece.
Aristides EliopoulosSchool of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Konstantina GeorgilaSchool of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Agostinho CarvalhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0001-8935-8030
Oliver KurzaiInstitute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Shivaprakash Mandya RudramurthyDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.ORCID 0000-0002-9097-9253
Caroline ElieUnit of Clinical Research, AP-HP, University Necker Hospital, Paris, France.
Fanny LanternierService de Maladies Infectieuses et Tropicales, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cite, Paris, France.
Kyriakos PetratosInstitute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, Greece.ORCID 0000-0003-0876-1835
Victoriano GarreDepartamento de Genética y Microbiología, Facultad de Biología, Universidad de Murcia, Murcia, Spain.ORCID 0000-0001-7605-1726
Elias DrakosSchool of Medicine, University of Crete, Voutes, Heraklion, Greece.
Johan MaertensDepartment of Hematology, University Hospitals Leuven, Leuven, Belgium.
Vincent M BrunoDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.
Dimitrios P KontoyiannisDepartment of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Coral BarbasCentro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Madrid, Spain.ORCID 0000-0003-4722-491X
Sameh S M SolimanResearch Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.ORCID 0000-0002-7691-615X
Ashraf S IbrahimDivision of Infectious Diseases, The Lundquist Institute for Biomedical Innovation, Harbor-University of California at Los Angeles (UCLA) Medical Center, Torrance, CA, USA.ORCID 0000-0003-3787-8530
Georgios ChamilosSchool of Medicine, University of Crete, Voutes, Heraklion, Greece. hamilos@imbb.forth.gr.ORCID 0000-0002-7987-4055

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FRASER, CLAIRE M., RASKO, DAVID A · 2014 to 2023
$36.5M
Novel Toxins and Receptors in Mucormycosis Pathogenesis and TreatmentR01AI063503 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI IBRAHIM, ASHRAF S. · 2006 to 2025
$7.3M
Therapeutic targeting of growth factor receptors to treat MucormycosisR01AI141360 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BRUNO, VINCENT MICHAEL · 2019 to 2023
$2.5M
NIAID NIH HHS R01 AI063503NIAID NIH HHS R01 AI141360NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

Mucormycosis is an emerging, life-threatening human infection caused by Mucorales fungi

Indexed as

AlbuminsMucoralesMucormycosisAnimalsAntifungal AgentsFatty Acids, NonesterifiedFemaleHost-Pathogen InteractionsHumansMaleMiceOxidation-ReductionVirulence FactorsAlbuminsAntifungal AgentsFatty Acids, NonesterifiedVirulence Factors

Identifiers

PMID41501454
PMCPMC12804082

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.