ArticleNature2026
Neuro-epithelial circuits promote sensory convergence and intestinal immunity.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- The SP-MrgprX2 Axis in Allergic Rhinitis: a Neuro-immune Paradigm Beyond IgE-mediated Inflammation.Clinical reviews in allergy & immunology · 2026Review
- Roles for specialized secretory epithelial cells in inflammatory bowel disease.Current opinion in gastroenterology · 2026Review
- Gastrointestinal tuft cells: Recent insights and next questions.Science immunology · 2026Review
- γδ T Cell-Mediated Neuroimmune Interactions in Skin Inflammation and Allergy.Clinical reviews in allergy & immunology · 2026Review
- Intestinal stem cells as innate immune sentinels: coupling environmental sensing to epithelial adaptation.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Wen Zhang *Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Elizabeth R Emanuel *Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Hiroshi YanoJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-3098-2629
Jazib UddinJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0001-5303-5213
Stephen GaudinoJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Zili XieAllen Discovery Center for Neuroimmune Interactions, New York, NY, USA.ORCID 0000-0002-9060-6780
Hiroshi IchiseLymphocyte Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-5187-810X
Zhen WangAllen Discovery Center for Neuroimmune Interactions, New York, NY, USA.
Maureen N CowanAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0001-6842-8175
Mengze LyuJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-8509-7969
Xiaoxiao HouJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0009-0005-6361-4047
Peng ZengJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Elin HuJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0009-0001-9444-415X
Victoria Ribeiro de GodoyJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Alex GrierJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Nina EstepAllen Institute for Immunology, Seattle, WA, USA.ORCID 0009-0000-3005-8885
Julien R IshibashiAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0002-7273-8034
Stephanie Anover-SombkeAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0002-8530-8068
Peter J SkeneAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0001-8965-5326
Toufic MayassiBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Ramnik J XavierBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-5630-5167
Ronald N GermainLymphocyte Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0003-1495-9143
Anna-Maria GlobigAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0002-5236-7459
Maximilian HeegAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0002-9594-1377
Ananda W GoldrathAllen Institute for Immunology, Seattle, WA, USA.
Brian S KimAllen Discovery Center for Neuroimmune Interactions, New York, NY, USA.ORCID 0000-0002-8100-7161
Hongzhen HuAllen Discovery Center for Neuroimmune Interactions, New York, NY, USA.
David ArtisJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA. dartis@med.cornell.edu.ORCID 0000-0002-1753-4100
Funding
Regulation of protective immunity following enteric viral infectionU01AI095608 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID, SONNENBERG, GREGORY F · 2011 to 2025
$11.0MMicrobiota-derived metabolites and the regulation of host immunity and inflammation (Diversity Supplement)R01AI172027 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI David Artis, Chun-Jun Guo · 2022 to 2026
$4.4MNeuroimmune Regulation of Atopic DermatitisR01AR070116 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2016 to 2021
$3.8MRegulation and function of innate lymphoid cells in the gutR01AI095466 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2011 to 2022
$3.7MTARGETING THE TRANSIENT RECEPTOR POTENTIAL CHANNELS TO IMPROVE BOWEL DYSFUNCTIONR01DK103901 · NIDDK · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2015 to 2023
$3.4MNeuropeptide-mediated regulation of antihelminth immunityR01AI151599 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI ARTIS, DAVID, SIRACUSA, MARK CHRISTOPHER · 2020 to 2024
$3.2MRegulation of IgE and Atopic ItchR01AI167933 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CONROY, MICHELLE E, KIM, BRIAN · 2022 to 2025
$3.2MNeuro-immune regulation of intestinal inflammationR01DK126871 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2020 to 2024
$3.2MT cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0MDietary Regulation of Intestinal Inflammation and RepairR01DK132244 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID, GUO, CHUN-JUN · 2022 to 2025
$2.7MDeciphering the Piezo2-Merkel cell signaling mechanisms in itchR01AR077183 · NIAMS · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2020 to 2024
$2.6MNatural Killer Cell Regulation of Skin InflammationR01AR077007 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2021 to 2025
$2.5MNCI NIH HHS K99 CA290052NIAID NIH HHS K99 AI180354NIAID NIH HHS R01 AI095466NIAID NIH HHS R01 AI151599NIAID NIH HHS R01 AI167933NIAID NIH HHS R01 AI172027NIAID NIH HHS R21 AI167047NIAID NIH HHS R37 AI067545NIAID NIH HHS U01 AI095608NIAMS NIH HHS R01 AR070116NIAMS NIH HHS R01 AR077007NIAMS NIH HHS R01 AR077183NIDDK NIH HHS K99 DK138293NIDDK NIH HHS K99 DK138295NIDDK NIH HHS R01 DK103901NIDDK NIH HHS R01 DK126871NIDDK NIH HHS R01 DK132244NIDDK NIH HHS R01 DK134773NIDDK NIH HHS R01 DK141106
Abstract
Type 2 inflammation at barrier surfaces is an evolutionarily conserved response that promotes immunity to helminth parasites, allergic inflammation and tissue repair
Indexed as
Epithelial CellsIntestinal MucosaIntestinesNociceptorsAnimalsCalcitonin Gene-Related PeptideCell DifferentiationCell ProliferationFemaleInflammationMaleMiceMice, Inbred C57BLSingle-Cell AnalysisStem CellsTRPV Cation ChannelsCalcitonin Gene-Related PeptideTRPV1 protein, mouseTRPV Cation Channels
Identifiers
What Socratic holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.