Evidence map›Paper›PMID 41501774›Full record

ArticleJournal of nanobiotechnology2026

Biomimetic PD-1-nanovesicles inducing tri-modal sonodynamic-chemo-immunotherapy for breast cancer therapy and lung metastasis inhibition.

Wenjin Lin, Zhenhu Lin, Fen Fu, Zhiyong Li, Haidong Dong, Leilei Liu, Xiaodong Xie, Xiujuan Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenjin Lin *Department of Ultrasound, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, China.
Zhenhu Lin *Department of Ultrasound, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, China.
Fen FuDepartment of Ultrasound, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, China.
Zhiyong LiDepartment of Ultrasound, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, China.
Haidong DongDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, 350001, Fujian, China.
Leilei LiuDepartment of Ultrasound, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, 350001, Fujian, China. liull8675@126.com.
Xiaodong XieFuzhou Marine Drug Discovery Industry Technology Innovation Center, Fuzhou Institute of Oceanography, Minjiang University, Fuzhou, 350108, Fujian, China. fantasyxiaodong@163.com.
Xiujuan ZhangDepartment of Ultrasound, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian, China. jenifer81@126.com.

Funding

Fujian Provincial Department of Science and Technology Guiding Science and Technology Planning Project 2024Y0022Joint Funds for the innovation of science and Technology, Fujian province 2024Y9307;2024Y9802;2023Y9202
6 · The paper itself

Abstract

backgroundCurrent cancer therapeutic approaches demonstrate constrained efficacy and fail to effectively address tumor metastasis, underscoring the critical need for innovative treatment modalities.

resultsIn this study, we developed an innovative PD-1

conclusionsThese findings establish PD-1-Au@DOX + US as a tri-modal approach for breast cancer treatment and metastasis prevention, providing an effective new clinical pathway.

Indexed as

Antineoplastic AgentsBiomimetic MaterialsBreast NeoplasmsGoldLung NeoplasmsMetal NanoparticlesProgrammed Cell Death 1 ReceptorAnimalsCell Line, TumorDoxorubicinFemaleHumansImmunotherapyMiceMice, Inbred BALB CReactive Oxygen SpeciesAntineoplastic AgentsDoxorubicinGoldProgrammed Cell Death 1 ReceptorReactive Oxygen SpeciesBreast cancerChemotherapyImmunotherapyMetastasis preventionSonodynamic therapy

Identifiers

PMID41501774
PMCPMC12870908

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.