Evidence mapPaperPMID 41502213Full record

ReviewBiochemical Society transactions2026

Leveraging AI for cell biology discovery.

Adriana Simizo, Mauro de Morais, Matheus Vesco, Helder Nakaya

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adriana SimizoHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID 0000-0002-3124-8936
Mauro de MoraisDepartment of Clinical and Toxicological Analyses, University of São Paulo, São Paulo, SP, Brazil.ORCID 0000-0003-4248-750X
Matheus VescoHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID 0000-0002-4107-1281
Helder NakayaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID 0000-0001-5297-9108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) has become a transformative tool in cell biology, driving discoveries through the analysis of complex biological data. This review explores the diverse applications of AI, including its impact on microscopy, imaging, drug discovery, and synthetic biology. AI methods have significantly advanced our ability to analyze cellular images at single-cell resolution, uncover complex patterns in biological data, and predict cellular responses to various stimuli. Deep learning approaches have improved cell segmentation and tracking, facilitated precise single-cell transcriptomics analysis, and enhanced our understanding of protein structures and interactions. The application of AI to high-throughput technologies has also enabled detailed modeling of cell behavior. Key challenges are addressed, such as data quality requirements, model interpretability, and the need to democratize AI tools for broader accessibility in biology. Finally, the review considers future directions, highlighting AI's potential to advance basic research and therapeutic applications.

Indexed as

Artificial IntelligenceCell BiologyAnimalsDrug DiscoveryHumansMicroscopySingle-Cell AnalysisSynthetic Biologyartificial intelligencecell biologydeep learningdrug discoverymicroscopyprotein structure predictionsingle-cell analysissynthetic biology

Identifiers

PMID41502213
PMCPMC12862965

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.