Association of erectile dysfunction and daily food thiamin intake among men in the USA.

Background: Erectile dysfunction (ED) is a common male health issue influenced by vascular and neurological factors. Although prior studies have linked micronutrients to ED, the role of thiamin (vitamin B Methods: In this study, data from two cycles (2001-2002, 2003-2004) of the National Health and Nutrition Examination Survey were used, which included information on daily riboflavin intake from food and self-reported ED. For the assessment of clinical ED, participants were categorised as those who reported being 'sometimes able' or 'never' to maintain an erection based on a single question. Daily food intake and consumption data were obtained through questionnaires and 24-hour recall interviews. The relationship between daily food thiamin intake and ED was analysed using logistic regression models and smooth curve fitting. Results: We found that higher food thiamin intake was significantly associated with lower incidence of hypertension, diabetes, coronary heart disease, stroke and ED (all p trend <0.05). Compared with participants with thiamin intake <1.3 μg, the full-adjusted ORs and 95% CIs for participants with thiamin intake >1.3 μg were 0.782 (0.651 to 0.940) (p<0.05). These findings suggest that dietary thiamin intake may play a protective role in the development of ED and other cardiometabolic disorders. Increasing thiamin consumption through dietary modification or supplementation could represent a potential strategy for ED prevention and management. Conclusions: Greater dietary thiamin intake demonstrated a statistically significant association with reduced incidence of ED. Our findings suggest that a lower intake of thiamin is an independent risk factor with ED. We can consider increasing the intake of thiamine in daily food.