Evidence map›Paper›PMID 41503488›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Obese patient imaging: improved dose efficiency with photon-counting CT.

Leening P Liu, Kai Mei, Shobhit Sharma, Steven Ross, Sandra S Halliburton, Richard Thompson, Naruomi Akino, Ali H Dhanaliwala, Leonid Roshkovan, Harold I Litt and 1 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Leening P LiuDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-0560-5394
Kai MeiDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-6429-7830
Shobhit SharmaCanon Medical Research USA, Vernon Hills, IL.ORCID 0000-0002-1592-5968
Steven RossCanon Medical Research USA, Vernon Hills, IL.
Sandra S HalliburtonCanon Healthcare USA, Cleveland, OH.ORCID 0000-0002-1469-7043
Richard ThompsonCanon Healthcare USA, Cleveland, OH.
Naruomi AkinoCanon Medical Systems Corporation, Otawara, Japan.ORCID 0000-0002-7413-2095
Ali H DhanaliwalaDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-2152-700X
Leonid RoshkovanDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-8890-8835
Harold I LittDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-2394-6053
Peter B NoëlDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0002-9671-6171

Funding

PixelPrint: a 3D printing platform for creating lifelike patient-based CT phantomsR01EB035092 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Peter B Noel · 2024 to 2026
$1.8M
NIBIB NIH HHS R01 EB035092
6 · The paper itself

Abstract

Objective: To evaluate the dose efficiency of cadmium-zinc-telluride (CZT) based photon-counting CT (PCCT) compared to energy-integrating detector CT (EID-CT) across phantom sizes. Methods: A patient-specific 3D-printed pancreas phantom and a phantom with tissue mimicking inserts were placed in extension rings corresponding to the 50 Results: PCCT demonstrated reduced noise compared to EID-CT across all phantom sizes and doses with average noise reductions of 22%, 23%, 25%, and 28% for the 50 Conclusions: PCCT exhibited superior dose efficiency compared to EID-CT across a range of phantom sizes. The enhanced dose efficiency enables both noise reduction and potential dose reduction for the imaging of obese patients and low-dose imaging applications.

Indexed as

diagnostic imagingradiation dosageX-ray computed tomography

Identifiers

PMID41503488
PMCPMC12772687

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.