Evidence map›Paper›PMID 41503555›Full record

ReviewReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2025

Influence of androgen deprivation therapy on physical performance and muscle strength in prostate cancer patients - a systematic review.

Zuzanna Szarzyńska, Igor Barczak, Karol Giermek, Aleksandra Garczyk, Marcin Mardas, Marta Stelmach-Mardas

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. FocaSaBra: a prospective phase II study on focal salvage brachytherapy for prostate cancer recurrence after radiotherapy - trial design.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zuzanna SzarzyńskaDepartment of Obesity Treatment, Metabolic Diseases and Clinical Dietetics, Poznan University of Medical Sciences, Poznan, Poland.
Igor BarczakDepartment of Obesity Treatment, Metabolic Diseases and Clinical Dietetics, Poznan University of Medical Sciences, Poznan, Poland.
Karol GiermekDepartment of Obesity Treatment, Metabolic Diseases and Clinical Dietetics, Poznan University of Medical Sciences, Poznan, Poland.
Aleksandra GarczykDepartment of Obesity Treatment, Metabolic Diseases and Clinical Dietetics, Poznan University of Medical Sciences, Poznan, Poland.
Marcin MardasStudent Scientific Society at the Poznan University of Medical Sciences, Poznan, Poland.
Marta Stelmach-MardasDepartment of Obesity Treatment, Metabolic Diseases and Clinical Dietetics, Poznan University of Medical Sciences, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the impact of androgen deprivation therapy (ADT) on muscle strength and physical performance in prostate cancer (PC) patients. The systematic search was carried out across four databases: PubMed, Embase, Web of Science, and Scopus. Out of 5239 studies, 6 were included, where the standardized functional tests assessing functional mobility were used. The protocol was registered on PROSPERO. Data indicated that the grip strength decreases most rapidly at the beginning of ADT therapy and does not return to its initial values. The gait speed decreases with the duration of ADT and indicates that the patients are at increased risk of adverse outcomes. According to the Short Physical Performance Battery and the time Up and Go test results PC patients present good performance and good mobility. Changes in muscle strength and physical performance in PC patients undergoing ADT are visible and need attention of professionals to prevent further body composition changes.

Indexed as

androgen deprivation therapymuscle massnutritional statusprostate cancersarcopenia

Identifiers

PMID41503555
PMCPMC12772949

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.