Evidence map›Paper›PMID 41503704›Full record

ArticleGut microbes2026

The role of gut microbiota in chronic intestinal pseudo-obstruction: exploring fecal microbiota transplantation as a treatment option.

Giada De Palma, Anna Costanzini, Vidhyalakshmi Mohan, Sacha Sidani, Zarwa Saqib, Marc Pigrau, Jun Lu, Natalia Causada Calo, Ines Pinto-Sanchez, Elena F Verdu and 6 more

Abstract read
In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giada De PalmaFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0002-2063-7741
Anna CostanziniDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-8644-1135
Vidhyalakshmi MohanFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.
Sacha SidaniFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0001-9669-0082
Zarwa SaqibFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.
Marc PigrauFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.
Jun LuFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.
Natalia Causada CaloFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0003-3828-1031
Ines Pinto-SanchezFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0002-9040-9824
Elena F VerduFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0001-6346-2665
Margaret MarconDivision of Gastroenterology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.ORCID 0000-0003-3850-1989
Giovanni BarbaraIRCCS University Hospital, Bologna, Italy; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy.
Vincenzo StanghelliniIRCCS University Hospital, Bologna, Italy; Department of Medical and Surgical Science, University of Bologna, Bologna, Italy.
Roberto De GiorgioDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Stephen M CollinsFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0003-1613-3732
Premysl BercikFarncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0001-8707-1781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic intestinal pseudo-obstruction (CIPO) is characterized by bowel dilation and obstructive symptoms without any structural blockage. Although the microbiota is known to affect gastrointestinal function, its role in CIPO is poorly understood. We aimed to characterize the CIPO microbiota, investigate its role in disease expression and explore the therapeutic role of fecal microbiota transplantation (FMT). CIPO patients (

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeIntestinal Pseudo-ObstructionAdultAnimalsBacteriaChronic DiseaseFecesFemaleGastrointestinal TransitHumansMaleMiceMiddle AgedRNA, Ribosomal, 16SRNA, Ribosomal, 16SChronic intestinal pseudo-obstructionfecal microbiota transplantationmicrobiomesevere constipation

Identifiers

PMID41503704
PMCPMC12785189

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.