Evidence map›Paper›PMID 41504168›Full record

ArticleAmerican journal of hematology2026

Mechanistic Consequences of Piezo1 Gain-of-Function Variants for Decreased Red Cell Survival in Hereditary Xerocytosis.

Asya Makhro, Rick Huisjes, Elena Seiler, Min Qiao, Marije Bartels, Inga Hegemann, Patrick Eppenberger, Nicole Bender, Isabel Dorn, Anna Bogdanova and 2 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Asya MakhroEvolutionary Pathophysiology, Institute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.
Rick HuisjesRed Blood Cell Research Group, Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, the Netherlands.
Elena SeilerRed Blood Cell Research Group, Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
Min QiaoDynamics of Fluids, Experimental Physics, Saarland University, Saarbrücken, Germany.ORCID https://orcid.org/0000-0002-2734-6824
Marije BartelsCenter for Benign Hematology, Thrombosis and Hemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, the Netherlands.
Inga HegemannDepartment of Medical Oncology and Hematology, University Hospital and University of Zürich, Zürich, Switzerland.
Patrick EppenbergerEvolutionary Pathophysiology, Institute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.
Nicole BenderEvolutionary Pathophysiology, Institute of Evolutionary Medicine, University of Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0002-3838-587X
Isabel DornDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Graz, Graz, Austria.
Anna BogdanovaRed Blood Cell Research Group, Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
Richard van WijkRed Blood Cell Research Group, Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, the Netherlands.
Lars KaestnerDynamics of Fluids, Experimental Physics, Saarland University, Saarbrücken, Germany.

Funding

Deutsche Forschungsgemeinschaft 522062907European Community 101120168European Community 602121FWF Austria 10.55776/I6572Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 215931
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41504168
PMCPMC12868995

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.