Evidence map›Paper›PMID 41504172›Full record

ArticleChemistry & biodiversity2026

Optimizing Nanopriming Duration: Chitosan-Stabilized Iron Oxide Enhances Lettuce Seedling Performance and Cost-Effectiveness.

Nurfarwizah Adzuan Hafiz, Anca Awal Sembada, Mohamed Syazwan Osman, Noor Fitrah Abu Bakar, Mohamad Sufian So'aib, I Wuled Lenggoro

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nurfarwizah Adzuan HafizEMZI-UiTM Nanoparticles Colloids & Interface Industrial Research Laboratory (NANO-CORE), Faculty of Chemical Engineering, Universiti Teknologi MARA, Cawangan Pulau Pinang, Permatang Pauh Campus, Permatang Pauh, Malaysia.
Anca Awal SembadaSchool of Life Sciences and Technology, Institut Teknologi Bandung (ITB), Bandung, Indonesia.ORCID https://orcid.org/0000-0002-1774-8344
Mohamed Syazwan OsmanEMZI-UiTM Nanoparticles Colloids & Interface Industrial Research Laboratory (NANO-CORE), Faculty of Chemical Engineering, Universiti Teknologi MARA, Cawangan Pulau Pinang, Permatang Pauh Campus, Permatang Pauh, Malaysia.ORCID https://orcid.org/0000-0003-3502-4769
Noor Fitrah Abu BakarFaculty of Chemical Engineering, Universiti Teknologi MARA, Shah Alam, Malaysia.ORCID https://orcid.org/0000-0003-0270-424X
Mohamad Sufian So'aibEMZI-UiTM Nanoparticles Colloids & Interface Industrial Research Laboratory (NANO-CORE), Faculty of Chemical Engineering, Universiti Teknologi MARA, Cawangan Pulau Pinang, Permatang Pauh Campus, Permatang Pauh, Malaysia.ORCID https://orcid.org/0000-0001-8619-8780
I Wuled LenggoroDepartment of Applied Physics and Chemical Engineering, Graduate School of Engineering, Tokyo University of Agriculture and Technology (TUAT), Koganei, Japan.ORCID https://orcid.org/0000-0002-0048-8486

Funding

Fundamental Research Grant Scheme FRGS/1/2022/STG05/UITM/02/10Ministry of Higher Education, Malaysia
6 · The paper itself

Abstract

Climate change and nutrient limitations increasingly hinder seed germination and early seedling establishment, highlighting the need for sustainable enhancement strategies. This study evaluates a green nanopriming approach using chitosan-stabilized iron oxide nanoparticles synthesized via an aqueous, low-energy co-precipitation process that employs biodegradable chitosan and avoids hazardous reagents, fully aligning with green chemistry principles. Lettuce seeds were primed in a 1 ppm nanoparticle suspension for 2, 6, 8, 16, and 24 h to identify the optimal priming duration. Chitosan markedly improved nanoparticle dispersion and colloidal stability, producing a strongly positive surface charge (+35.5 mV) that enhanced nanoparticle-seed interactions. The 8-h priming treatment yielded the greatest improvements, achieving a germination rate of 96.67% alongside the highest shoot and root elongation and biomass accumulation. Longer exposures (16 and 24 h) reduced performance, suggesting potential overstimulation or early metabolic imbalance. These enhancements likely arise from improved iron bioavailability, nanoparticle stability, and stimulation of early metabolic activation. A pilot-scale cost assessment demonstrated excellent economic feasibility, with production costs of only $4.40 per 10-L batch, supporting scalability for agricultural use. Overall, optimizing nanopriming duration using chitosan-stabilized iron oxide nanoparticles offers a sustainable, economical, and environmentally responsible approach to strengthen crop establishment under stress.

Indexed as

ChitosanCost-Benefit AnalysisFerric CompoundsLactucaMagnetic Iron Oxide NanoparticlesSeedlingsGerminationParticle SizeChitosanFerric Compoundsferric oxidechitosan‐stabilized iron oxideeconomic feasibilitynano‐biointerfacenanoparticlesnanopriming durationseed germination

Identifiers

PMID41504172
PMCPMC13420255

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.