Evidence map›Paper›PMID 41504756›Full record

ArticleMedical care2026

Lessons Learned From Using PCORnet® to Support the Pathways to Cardiovascular Disease Prevention and Impact of Specialty Referral Among People With HIV From Underrepresented Racial and Ethnic Groups in the Southern United States (PATHWAYS Study).

Keith Marsolo, Karen Chiswell, Gretchen Sanders, Darcy Louzao, Thomas Phillips, Nwora Lance Okeke, Eric G Meissner, April Pettit, Caryn Morse, Gerald Bloomfield

Abstract read
In one paragraph

Article in Medical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keith MarsoloDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.ORCID 0000-0002-4416-1549
Karen ChiswellDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Gretchen SandersDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Darcy LouzaoDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Thomas PhillipsDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Nwora Lance OkekeDepartment of Medicine, Duke University School of Medicine, Durham, NC.
Eric G MeissnerDepartment of Medicine, Medical University of South Carolina, Charleston, SC.
April PettitDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Caryn MorseDepartment of Infectious Diseases, Wake Forest University School of Medicine, Winston-Salem, NC.
Gerald BloomfieldDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Pathways to cardiovascular disease prevention and impact of specialty referral in under-represented racial/ethnic minorities with HIVR01MD013493 · NIMHD · DUKE UNIVERSITY · PI BLOOMFIELD, GERALD SAMUEL · 2018 to 2022
$3.3M
NCATS NIH HHS UL1 TR002243NCATS NIH HHS UL1 TR002553NIAID NIH HHS P30 AI110527NIMHD NIH HHS R01 MD013493
6 · The paper itself

Abstract

objectiveThe PATHWAYS Study utilized data from the PCORnet® Common Data Model (CDM) at 4 sites participating in the STAR Clinical Research Network to assess the frequency of cardiology encounters for under-represented racial and ethnic minority group people living with Human Immunodeficiency Virus and to evaluate the determinants associated with specialty encounters from 2014 to 2020. This study dealt with several factors that other projects leveraging PCORnet might face. We describe benefits of working with the network, challenges, and recommendations for future study teams.

methodsPATHWAYS used a mix of queries through the study, including study-specific data quality and analytic queries. A "sidecar" table was created for the PCORnet® Common Data Model to support the inclusion of referral data. Linkage to the National Death Index was incorporated into the study to allow for more comprehensive information on participant deaths.

resultsData quality assessments identified several issues over the course of the study that needed to be addressed by the data teams at each site. The referral data proved not to be robust enough to support the proposed analyses, so an alternative strategy was required that leveraged encounter information. The National Data Index included information on participant deaths that were not part of each site's PCORnet® CDM.

conclusionIncorporating study-specific data characterization into the overall analysis plan is important. When working with new data, or variables not commonly used within studies, teams should include time and effort for site resources to investigate their local clinical workflows and potential mappings to the PCORnet® CDM.

Indexed as

Cardiovascular DiseasesEthnicityHIV InfectionsMinority GroupsReferral and ConsultationAdultFemaleHumansMaleMiddle AgedRacial GroupsUnited Statescommon data modelelectronic health recordsHIVPCORnet

Identifiers

PMID41504756
PMCPMC12783337

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.