Evidence map›Paper›PMID 41504965›Full record

ArticleEuropean journal of pediatrics2026

Early mobilization in pediatric critical care and parental psychological outcomes 3-6 months after discharge-a pilot study.

Stijn van den Munckhof, Emma Meijer, Suus Litjens, Erwin Ista, Nienke M Maas-van Schaaijk, Annelies van Zwol

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Article in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Stijn van den MunckhofDepartment of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Emma MeijerDepartment of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Suus LitjensDepartment of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Erwin IstaDepartment of Neonatal and Pediatric Intensive Care, Division of Pediatric Intensive Care, Erasmus MC-Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Nienke M Maas-van SchaaijkDepartment of Medical Psychology, University Hospital Radboudumc, Nijmegen, The Netherlands.
Annelies van ZwolDepartment of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. Annelies.vanzwol@radboudumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advancements in care for critically ill children have lowered mortality but increased morbidity in survivors. Post-intensive care syndrome (PICS) in children including their families (PICS-p) underscores the need for interventions to mitigate long-term effects. Early mobilization shows promising results in adults; however, evidence in pediatrics is limited. Enhanced parental involvement may contribute to improved long-term psychological outcomes. This pilot study examines the impact of an early mobilization program on parental stress and psychological health after admission on a pediatric intensive care unit (PICU). This single-center pilot study was conducted between 2021 and 2024 at the PICU of the Radboudumc University Hospital. Data of parents of patients admitted before (n = 45) and after (n = 45) implementation of an early mobilization bundle (December 2022) were compared. Parental psychological health outcomes were assessed using validated post-traumatic stress disorder (PTSD), burden scales, anxiety, and depression questionnaires, completed within 3-6 months after admission. Ninety patients were enrolled. There was no significant difference between pre- and post-intervention groups, but a trend towards lower parental experienced distress score (2.2 (IQR 0-8) vs 4.0 (IQR0-9) p 0.08) and lower depression scores in fathers (8.5 (IQR 8-15) vs 9.5 (8-32), p 0.07) in the post-intervention group was observed.

conclusionAlthough no significant effect of early mobilization on parental psychological health was found, a trend towards a positive effect on the experienced distress scale and the paternal depression score emerged. A future nationwide study, on larger scale, is intended to further evaluate these findings. WHAT IS KNOWN: • Early mobilization in adult critical care improves patient recovery and reduces ICU-acquired weakness and improves physical and psychological outcomes. • In the pediatric critical care setting, early mobilization is considered safe and feasible, but research on long-term effects is limited. WHAT IS NEW: • This study focuses on the long-term effects of early mobilization on parental psychological health. • Findings indicate no significant difference between pre- and post-intervention group, but a positive trend of early mobilization on experienced distress scale and paternal depression score.

Indexed as

Critical CareCritical IllnessEarly AmbulationParentsStress, PsychologicalAdolescentAdultAnxietyChildChild, PreschoolDepressionFemaleHumansInfantIntensive Care Units, PediatricMaleCritical careLong-termMobilizationOutcomePediatricPsychological

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.