Evidence map›Paper›PMID 41505072›Full record

ReviewCurrent medical science2026

Graphene Quantum Dots in Cancer Diagnostics and Therapeutics: Advances in Biosensing, Imaging, and Treatment Applications.

Manish R Bhise, Vishal Trivedi, Suprabha Devi, Arpan Kumar Tripathi, Jayendra Kumar, Sunand Katta, Adarsh Vishnu Raval, Shamim Shamim, Ram Kumar, Pawan Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manish R BhiseDepartment of Pharmaceutics, SGSPS Institute of Pharmacy, Sant Gadge Baba Amravati University, Amravati, India.
Vishal TrivediDepartment of Pharmacy, Madhav University, Pindwara, India.
Suprabha DeviDepartment of Pharmacology, Institute of Technology and Management, Gorakhpur Industrial Development Authority (GIDA), Gorakhpur, India.
Arpan Kumar TripathiFaculty of Pharmaceutical Sciences, Shri Shankaracharya Technical Campus, Bhilai, India.
Jayendra KumarDepartment of Pharmaceutical Chemistry, SRM Modinagar College of Pharmacy, SRM Institute of Science and Technology, Delhi-NCR Campus, Modinagar, Uttar Pradesh, India.
Sunand KattaSchool of Pharmacy, Anurag University, Venkatapur, India.
Adarsh Vishnu RavalDr. Bhanuben Nanavati College of Pharmacy, Mumbai, India.
Shamim ShamimIIMT College of Medical Sciences, IIMT University, Ganga Nagar, India.
Ram KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India.
Pawan KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, India. pawankamiya@yahoo.in.ORCID http://orcid.org/0000-0001-6549-9779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene quantum dots (GQDs) have emerged as promising nanomaterials in cancer therapy because of their unique physicochemical properties. This review comprehensively analyzes the roles of GQDs in cancer diagnostics and treatment, highlighting their biocompatibility, tunable photoluminescence, and surface functionalization capabilities. GQDs exhibit minimal toxicity, efficient cellular uptake, and favorable biodistribution, making them suitable for targeted drug delivery, photothermal therapy (PTT), and photodynamic therapy (PDT). Their intrinsic fluorescence also enables real-time bioimaging, supporting theranostic applications. This study explores their mechanisms of action, including reactive oxygen species (ROS) generation, heat-induced ablation, and pH-responsive drug release. GQDs have demonstrated efficacy across various cancers, such as breast, lung, brain, liver, and pancreatic cancers, through enhanced drug/gene delivery, biosensing, and image-guided therapy. Despite encouraging preclinical results, challenges related to toxicity profiling, standardization, regulatory frameworks, and scalability remain significant barriers to clinical translation. This review emphasizes the therapeutic versatility of GQDs and underscores the need for further research to overcome translational hurdles and realize their full potential in personalized cancer care.

Indexed as

Biosensing TechniquesGraphiteNeoplasmsQuantum DotsAnimalsDrug Delivery SystemsHumansPhotochemotherapyReactive Oxygen SpeciesTheranostic NanomedicineGraphiteReactive Oxygen SpeciesBrain tumorsBreast cancerCancer therapyDrug deliveryGraphene quantum dots (GQDs)Lung cancerNanomaterial

Identifiers

PMID41505072

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.