Evidence map›Paper›PMID 41505488›Full record

ArticlePLoS neglected tropical diseases2026

Splenic accumulation of intact Plasmodium ovale sensu lato-infected red blood cells in a patient presenting with splenic rupture.

Ghania Benabdelmoumen, Oula Itani, Valentin Joste, Sandrine Houzé, David Hardy, Florent Bavozet, Moussa Sylla, Steven Kho, Nicholas M Anstey, Paul Henri Consigny and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ghania BenabdelmoumenInstitut Pasteur, Centre Médical, Centre d'Infectiologie Necker Pasteur, Paris, France.
Oula ItaniInstitut Pasteur, Centre Médical, Centre d'Infectiologie Necker Pasteur, Paris, France.ORCID https://orcid.org/0009-0008-9392-7900
Valentin JosteUniversité Paris Cité, Inserm, EFS, BIGR U1134, Paris, France.
Sandrine HouzéUniversité Paris Cité, IRD, MERIT, Paris, France.
David HardyInstitut Pasteur, Experimental Neuropathology Unit, Paris, France.
Florent BavozetMédecine Intensive Réanimation, CH de Dreux, Dreux, France.
Moussa SyllaChirurgie viscérale, digestive et métabolique, CH de Dreux, Dreux, France.
Steven KhoGlobal and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia.
Nicholas M AnsteyGlobal and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia.
Paul Henri ConsignyInstitut Pasteur, Centre Médical, Centre d'Infectiologie Necker Pasteur, Paris, France.
Abdoulaye SissokoUniversité Paris Cité, Inserm, EFS, BIGR U1134, Paris, France.
Pierre BuffetInstitut Pasteur, Centre Médical, Centre d'Infectiologie Necker Pasteur, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 35-year-old man had splenic rupture just after starting antimalarial treatment with atovaquone-proguanil followed by artesunate for acute Plasmodium ovale sensu lato infection. Spleen histology showed a 10-fold accumulation of intact P. ovale s.l.-infected erythrocytes in the spleen parenchyma compared to the general circulation. Infected erythrocytes also accumulated in small extra-splenic blood vessels, suggesting cytoadherence.

Indexed as

ErythrocytesMalariaPlasmodium ovaleSpleenSplenic RuptureAdultAntimalarialsArtemisininsArtesunateAtovaquoneDrug CombinationsHistocytochemistryHumansMaleProguanilAntimalarialsArtemisininsArtesunateAtovaquoneatovaquone, proguanil drug combinationDrug CombinationsProguanil

Identifiers

PMID41505488
PMCPMC12829925

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.