Evidence map›Paper›PMID 41506748›Full record

Observational studyBMJ open2026

Breastfeeding and later depression and anxiety in mothers in Ireland: a 10-year prospective observational study.

Catherine McNestry, Sharleen L O'Reilly, Patrick J Twomey, Rachel K Crowley, Sophie Callanan, Alice Kasemiire, Alexander Douglass, Anna Delahunt, Fionnuala M McAuliffe

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catherine McNestryUCD Perinatal Research Centre, National Maternity Hospital, Dublin, Ireland.ORCID http://orcid.org/0000-0003-3459-0558
Sharleen L O'ReillyUCD Perinatal Research Centre, National Maternity Hospital, Dublin, Ireland.ORCID http://orcid.org/0000-0003-3547-6634
Patrick J TwomeyDepartment of Clinical Pathology, St Vincent's University Hospital, Dublin, Ireland.
Rachel K CrowleySchool of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
Sophie CallananUCD Perinatal Research Centre, National Maternity Hospital, Dublin, Ireland.
Alice KasemiireCentre for Support and Training in Analysis and Research, University College Dublin, Dublin, Ireland.
Alexander DouglassSchool of Public Health, Physiotherapy & Sports Science, University College Dublin, Dublin, Ireland.
Anna DelahuntUCD Perinatal Research Centre, National Maternity Hospital, Dublin, Ireland.
Fionnuala M McAuliffeUCD Perinatal Research Centre, National Maternity Hospital, Dublin, Ireland fionnuala.mcauliffe@ucd.ie.ORCID http://orcid.org/0000-0002-3477-6494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAlthough breastfeeding is associated with lower postnatal depression and anxiety, limited research exists regarding long-term maternal mental health outcomes. This study examined the association between breastfeeding and depression and anxiety in women of later reproductive age (mid 30s to menopause).

designThis was a 10-year prospective longitudinal cohort study. Self-reported questionnaires were used to collect lifetime breastfeeding behaviour at 10 years, and health history including depression, anxiety and medication use was collected at each study timepoint.

settingA tertiary level maternity hospital in Dublin, Ireland.

participants168 parous women from the ROLO Longitudinal Cohort with lifetime breastfeeding behaviour and health history data available at 10 years were included (22% of total cohort). Women currently pregnant or breastfeeding at 10-year follow-up were excluded.

resultsMean (SD) age at study end was 42.4 (3.8) years. 72.6% (n=122) of women reported ever breastfeeding. Median lifetime exclusive breastfeeding was 5.5 weeks (IQR 35.8, range 0-190). 37.5% of women (n=63) breastfed for ≥12 months over their lifetime. 13.1% (n=22) reported depression or anxiety at 10 years, and 20.8% (n=35) reported depression or anxiety over the whole study period. Ever breastfeeding was associated with less depression and anxiety at 10 years (OR 0.34, 95% CI 0.12 to 0.94, p=0.04). Ever breastfeeding, longer exclusive breastfeeding and lifetime breastfeeding ≥12 months were associated with lower depression and anxiety over the whole study period (ever breastfeeding OR 0.4, p=0.03; exclusive breastfeeding OR 0.98/week, p=0.03; lifetime breastfeeding ≥12 months OR 0.38, p=0.04).

conclusionThere may be a protective association between breastfeeding and self-reported depression and anxiety. Further studies are required to confirm the findings. TRIAL REGISTRATION NUMBER: ISRCTN54392969.

Indexed as

AnxietyBreast FeedingDepressionDepression, PostpartumMothersAdultFemaleHumansIrelandLongitudinal StudiesProspective StudiesSurveys and QuestionnairesMaternal medicineMENTAL HEALTHPhysiologyPostpartum Women

Identifiers

PMID41506748
PMCPMC13059848

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.