Evidence map›Paper›PMID 41507150›Full record

ReviewCell death & disease2026

Shedding light on the function of autophagy in complicated pregnancies.

Shuting Wan, Yuxing Huang, Huixia Yang

Abstract readReview
In one paragraph

Review in Cell death & disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shuting WanDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.ORCID http://orcid.org/0009-0002-6160-9744
Yuxing HuangDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China.ORCID http://orcid.org/0000-0002-1260-2725
Huixia YangDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China. yanghuixia@bjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a conserved degradation process in eukaryotic cells that is regulated by autophagy-related genes. During autophagy, lysosomes break down cytoplasmic proteins and damaged organelles. This process plays a pivotal role in cell growth and development, protection against metabolic stress and oxidative damage, and the maintenance of cellular homeostasis through the recycling of cellular components. Pregnancy encompasses crucial events such as decidualization, embryo implantation, and fetal growth. Abnormal autophagy has been implicated in several pregnancy complications and can significantly impact both maternal and fetal health. Understanding the relationship between autophagy and complicated pregnancies could open new avenues for potential therapeutic interventions to improve maternal and fetal outcomes. In this review, we summarize the intricate relationship between autophagy and pregnancy complications, elucidate the role of autophagy in gestation, and discuss the clinical significance of autophagy in mitigating or preventing pregnancy-related disorders.

Indexed as

AutophagyPregnancy ComplicationsAnimalsFemaleHumansLysosomesPregnancy

Identifiers

PMID41507150
PMCPMC12876986

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.