Evidence map›Paper›PMID 41507306›Full record

ArticleScientific reports2026

Percutaneous coronary intervention in nonagenarians with acute myocardial infarction: a 15-year population-based study.

Giancarlo Marenzi, Nicola Cosentino, Daniela Mele, Filippo Trombara, Giampaolo D'Aleo, Paolo Poggio, Olivia Leoni, Stefano Savonitto, Claudia Lucci, Alice Bonomi and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giancarlo MarenziCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy. giancarlo.marenzi@ccfm.it.
Nicola CosentinoCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Daniela MeleCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Filippo TrombaraCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Giampaolo D'AleoCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Paolo PoggioCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Olivia LeoniRegional Epidemiological Observatory, Lombardy Region, Milan, Italy.
Stefano SavonittoClinica San Martino, Malgrate, Italy.
Claudia LucciCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Alice BonomiCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.
Piergiuseppe AgostoniCentro Cardiologico Monzino IRCCS, Via Parea 4, Milan, 20138, Italy.

Funding

This work was supported by the Italian Ministry of Health and the Lombardy Region NET-2016-02364191
6 · The paper itself

Abstract

The use of percutaneous coronary intervention (PCI) in very elderly patients (> 90 years) with acute myocardial infarction (AMI) remains debated due to limited evidence and the presence of multimorbidity. This study evaluated the impact of PCI using data from the Lombardy Health Database (Italy) for AMI patients hospitalized between 2003 and 2018. Among 15,954 patients (median age 92; 71% female; 50% with ST-elevation myocardial infarction [STEMI]), 12% underwent PCI. In-hospital mortality was lower in PCI-treated patients (15% vs. 23%; P < 0.0001). Overall, one-year mortality (56%) and rehospitalization for acute heart failure (AHF) or AMI (19%) were also reduced among PCI patients (37% vs. 58% and 16% vs. 21%, respectively; P < 0.0001). These findings were consistent across both STEMI and non-ST-elevation myocardial infarction (NSTEMI) subgroups and were independent of comorbidities. Adjusted risk analyses and propensity score matching (1,950 patients per group) confirmed these benefits. The use of PCI increased significantly from 4% in 2003 to 22% in 2018, while in-hospital mortality declined from 22 to 19% (from 28 to 15% in the propensity-matched cohort). In conclusion, PCI was associated with significantly lower in-hospital and one-year mortality, as well as reduced rehospitalization rates, in AMI patients older than 90 years, regardless of comorbidities.

Indexed as

Myocardial InfarctionPercutaneous Coronary InterventionAged, 80 and overFemaleHeart FailureHospital MortalityHumansItalyMaleST Elevation Myocardial InfarctionTreatment OutcomeAcute myocardial infarction

Identifiers

PMID41507306
PMCPMC12847827

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.