Evidence map›Paper›PMID 41509113›Full record

ReviewAvicenna journal of phytomedicine

Effects of

Elmira Mohammadzadeh, Hassan Ghobadi, Jafar Mohammadshahi, Farzin Aslani, Mohammad Hossein Boskabady, Mohammad Reza Aslani

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elmira MohammadzadehLung Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Hassan GhobadiLung Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Jafar MohammadshahiLung Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Farzin AslaniDepartment of Orthopedics, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein BoskabadyApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza AslaniLung Diseases Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Evidence indicates that Materials and Methods: Studies done on NS and its components in animal models of OVA-induced asthma in all published articles up to July 2024 were searched in Scopus, PubMed, and Web of Science databases. The studies underwent assessment of methodological quality utilizing the 15-point CAMARADES checklist. MedCalc software was utilized for performing the data analysis. Results: Sixteen studies involving a total of 486 animals, with 243 in the intervention group and 243 in the ovalbumin-induced group were analyzed. In the meta-analysis results, it was shown that NS and its components notably decreased total white blood cells (WBC), eosinophils, lymphocytes, and neutrophils. Additionally, NS caused a shift in the half of the maximum effective concentration (EC50) curve to the right and decreased the maximum response rates and tracheal OVA-response in experimental animals. Conclusion: NS, and its components, could potentially influence asthma induced by OVA in animals by improving airway responsiveness and exhibiting anti-inflammatory and anti-oxidant properties. Consequently, it is recommended that NS be evaluated in additional clinical trials for patients with asthma.

Indexed as

Alpha-hederinAsthmaCarvacrolMeta-analysisNigella sativaOvalbuminThymolThymoquinone

Identifiers

PMID41509113
PMCPMC12777662

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.