Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Madison WilsonDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-9838-0798
Emily A MartinDepartment of Biology, Boston University, Boston, MA, USA.
Clara ChungDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.
Francesca PuppoDepartment of Pediatrics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Shira Klorfeld-AuslenderPicower Institute for Learning & Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0009-0009-4909-4611
Pierre BoucherDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.ORCID 0000-0003-0897-6457
Li-Huei TsaiPicower Institute for Learning & Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0003-1262-0592
Alysson R MuotriDepartment of Pediatrics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Duygu KuzumDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-2125-1285
Anna DevorDepartment of Biomedical Engineering, Boston University, Boston, MA, USA.ORCID 0000-0002-5143-3960
Timothy M O'SheaDepartment of Biomedical Engineering, Boston University, Boston, MA, USA.ORCID 0000-0002-0812-1179
Ella ZeldichDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.ORCID 0000-0002-9946-4512
Martin ThunemannDepartment of Biomedical Engineering, Boston University, Boston, MA, USA.ORCID 0000-0003-4139-079X
Funding
Single-cell approaches to deconvolution of disease-associated signalsU19MH107367 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALPAIN, SHELLEY L · 2015 to 2019
$15.0M
Brain pathology and function in a chronic mouse model of ZIKV transmissionR01NS105969 · NINDS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI MUOTRI, ALYSSON R., OLSON, STEVEN H · 2019 to 2023
$3.3M
Training Program in Quantitative Biology & Physiology (QBP)T32GM145455 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Darren Michael Roblyer · 2022 to 2026
$2.6M
Understanding neuronal dysfunction in Down Syndrome using assembloids and xenotransplanted cortical organoidsRF1AG088529 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI THUNEMANN, MARTIN, ZELDICH, ELLA · 2024 to 2024
$2.4M
The Impact of hiPSC-Derived Microglia in Human Brain Development in Health and DiseaseR01NS123642 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MUOTRI, ALYSSON R. · 2021 to 2025
$2.2M
Impact of prenatal inflammation on developing human brainR01HD107788 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Alysson R. Muotri · 2022 to 2026
$1.7M
The contribution of X-chromosome-linked genes to cellular phenotypes and AD-related pathology in Down SyndromeR21AG080269 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZELDICH, ELLA · 2023 to 2024
$454k
Biomaterial-directed patterning of xenografted brain organoids in-vivoF31NS141509 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Kate Elizabeth Herrema · 2025 to 2026
Human cortical organoids (hCOs) are three-dimensional neural cell aggregates that recapitulate certain structural and functional aspects of the developing human cortex. Xenotransplantation of hCOs into the rodent brain enables human-centric modeling of neurodevelopmental processes in a physiologically relevant environment. Here, we present a neurorecording toolkit for longitudinal structural and functional assessment of hCO xenografts as they mature
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
A neurorecording toolkit for longitudinal assessments of transplanted human cortical organoids · full record | Socratic