Evidence map›Paper›PMID 41509267›Full record

ArticlebioRxiv : the preprint server for biology2025

Biochemical and structural characterization of the RlaP family nucleotidyltransferase potentially involved in RNA repair.

Amy Carruthers, Shirin Fatma, Raven H Huang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amy CarruthersDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Shirin FatmaDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Raven H HuangDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Funding

Rescue and repair of stalled ribosome damaged by ribosome-specific ribotoxinsR01GM145060 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HUANG, RAVEN H · 2022 to 2025
$1.3M
Genome-wide profiling of RNA damage and repair in vivoU01GM120764 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HUANG, RAVEN H · 2016 to 2019
$1.1M
NIGMS NIH HHS R01 GM145060NIGMS NIH HHS U01 GM120764
6 · The paper itself

Abstract

Nucleotidyltransferases (NTases) of Polβsuperfamily are highly diverse and play many important biological functions. However, many families of NTases remain uncharacterized. Because of physical proximity of the genes encoding NTases of PF10127 family to those encoding RNA ligases involved in RNA repair, PF10127 family of NTases was named RlaP (RNA ligase-associating Polβ). Here we report comprehensive characterization of two RlaP from

Identifiers

PMID41509267
PMCPMC12776372

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.