Evidence map›Paper›PMID 41509422›Full record

ArticlebioRxiv : the preprint server for biology2026

Learning-dependent feedback by OLM interneurons shapes CA1 representations.

Evan P Campbell, Lisandro Martin, Jeffrey C Magee, Christine Grienberger

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evan P CampbellHoward Hughes Medical Institute, Baylor College of Medicine, Houston, TX, 77030.
Lisandro MartinBrandeis University, Department of Biology and Volen Center for Complex Systems, Waltham, MA, 02453.
Jeffrey C MageeHoward Hughes Medical Institute, Baylor College of Medicine, Houston, TX, 77030.
Christine GrienbergerBrandeis University, Department of Biology and Volen Center for Complex Systems, Waltham, MA, 02453.ORCID 0000-0002-7774-4062

Funding

Unraveling the synaptic and circuit mechanisms underlying a plasticity-driving instructive signalDP2MH136393 · NIMH · BRANDEIS UNIVERSITY · PI Christine Grienberger · 2023 to 2026
$2.4M
CRCNS: Coordinating learning by top-down gating of plasticity in dendritesRF1MH135576 · NIMH · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MILSTEIN, AARON D · 2025 to 2025
$1.2M
CRCNS: Coordinating learning by top-down gating of plasticity in dendritesR01MH135576 · NIMH · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MILSTEIN, AARON D · 2023 to 2024
$813k
NIMH NIH HHS DP2 MH136393NIMH NIH HHS R01 MH135576NIMH NIH HHS RF1 MH135576
6 · The paper itself

Abstract

Spatial learning depends on hippocampal CA1 place cell representations, which form rapidly through behavioral timescale synaptic plasticity (BTSP). BTSP is driven by dendritic plateau potentials proposed to arise from the interaction of an excitatory target signal from entorhinal cortex layer 3 (EC3) and inhibitory feedback reflecting the current CA1 population state. However, the cellular source of this feedback has remained unknown. Using two-photon Ca

Identifiers

PMID41509422
PMCPMC12776205

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.