Evidence map›Paper›PMID 41509535›Full record

ArticleResuscitation plus2026

Evaluation of ventilatory parameters reporting in large animal models of cardiac arrest: a scoping review.

Jean-Claude Li, Nicolas Segond, Arnaud Lesimple, Alice Hutin, Rebecca Goutchtat, Iann Drennan, Giuseppe Ristagno, Guillaume Debaty, Alain Cariou, Renaud Tissier and 1 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jean-Claude LiEcole nationale vétérinaire d'Alfort, IMRB, AfterROSC Network, 94700 Maisons-Alfort, France.
Nicolas SegondEmergency Department and Mobile Intensive Care Unit, University Hospital of Grenoble Alpes, Grenoble, France.
Arnaud LesimpleVent'Lab, Medical Intensive Care Unit, Angers University Hospital, Angers, France.
Alice HutinSAMU of Paris and Intensive Care Unit, Necker University Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris 75015, France.
Rebecca GoutchtatEcole nationale vétérinaire d'Alfort, IMRB, AfterROSC Network, 94700 Maisons-Alfort, France.
Iann DrennanDepartment of Family and Community Medicine, Division of Emergency Medicine, University of Toronto, Toronto, Ontario, Canada.
Giuseppe RistagnoDepartment of Pathophysiology and Transplantation, University of Milan, Italy.
Guillaume DebatyEmergency Department and Mobile Intensive Care Unit, University Hospital of Grenoble Alpes, Grenoble, France.
Alain CariouMedical ICU, Cochin Hospital, AP-HP Centre Université Paris Cité, AfterROSC Network, Paris, France.
Renaud TissierEcole nationale vétérinaire d'Alfort, IMRB, AfterROSC Network, 94700 Maisons-Alfort, France.
Jean-Christophe RichardVent'Lab, Medical Intensive Care Unit, Angers University Hospital, Angers, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ventilation is a critical determinant of cardiopulmonary resuscitation efficiency. Our goal was to evaluate how ventilatory parameters are reported during cardiopulmonary resuscitation in large animal models of cardiac arrest. Methods: A scoping review was conducted following the PRISMA-ScR guidelines, including studies referenced in Pubmed over the last decade (January 1st, 2015 to July 30th, 2025). The review followed the PCC approach: (P) population: large animal models of cardiac arrest; (C) concept: ventilatory settings and parameters during CPR; (C) context: studies aiming at describing or evaluating mechanical or manual ventilation during CPR in experimental conditions. The reporting of the animal characteristics, ventilatory settings and monitored parameters were extracted and analyzed descriptively. Results: We identified 111 relevant publications. Most of them used porcine models (79 %), with ventricular fibrillation being the most common method of cardiac arrest induction (59 %). Mechanical ventilation was predominant (75 %), with volume and pressure-controlled modes nearly equally represented. The reporting of critical ventilatory settings was inconsistent, with a percentage of appropriate reporting as follows: respiratory rate (88 %), fraction of inspired oxygen (83 %), positive end-expiratory pressure (49 %), tidal volume (83 %, among studies with volume-controlled ventilation), peak inspiratory pressure (92 %, among studies with pressure-controlled ventilation) and inspiratory to expiratory ratio (17 %, among all studies with mechanical ventilation). Reporting of measured ventilatory parameters during CPR was also limited with, e.g., EtCO Conclusions: This scoping review evidenced substantial variability and frequent omissions in the reporting of ventilatory settings and monitoring in large animal CPR studies. Updated recommendations could be useful to provide specific guidelines of reporting in the field.

Indexed as

Animal modelsCardiac arrestCardiopulmonary resuscitationManual ventilationTidal volumeVentilationVentilator

Identifiers

PMID41509535
PMCPMC12775993

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.