Evidence mapPaperPMID 41510033Full record

ArticleIranian journal of microbiology2025

Tight junctions expression is affected by active, inactive, and derivatives of

Farinaz Ghaderi, Zahra Hajebrahimi, Abolfazl Fateh, Fattah Sotoodehnejadnematalahi, Sara Ahmadi Badi, Somayeh Vaezijoze, Seyed Davar Siadat

Abstract read
In one paragraph

Article in Iranian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Farinaz GhaderiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Zahra HajebrahimiAir and Space Physiology Research Group, Aerospace Research Institute, Ministry of Science Research and Technology, Tehran, Iran.
Abolfazl FatehDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Fattah SotoodehnejadnematalahiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Sara Ahmadi BadiDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Somayeh VaezijozeDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Seyed Davar SiadatDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Tight junctions (TJs) in the gastrointestinal tract are comprised of various junctional proteins including Occludin and Zonula Occludens (ZO-1) that have a critical role in epithelial barrier function. Gut microbiota and their derived metabolites can maintain and regulate gut epithelial barrier integrity. Materials and Methods: In the present study, the effects of active, heat-inactivated, cell-free supernatant, and outer membrane vesicles (OMVs) of Results: Data have shown that both forms of the active (metabolically active, growing, and dividing state), and heat inactivated (by exposure to 56°C for 20 minutes) forms of the bacteria and the cell-free supernatant could affect the expression of Conclusion:

Indexed as

Akkermansia muciniphilaOccludinTight junctionsZonula occludens-1

Identifiers

PMID41510033
PMCPMC12777382

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.