Evidence map›Paper›PMID 41510201›Full record

ReviewJAC-antimicrobial resistance2026

Widening access to penicillin allergy assessment in the United Kingdom-a proposed implementation plan for the National Health Service (NHS).

Catherine E Porter, Caity Roleston, Claire Bethune, Jenny Boards, Colin S Brown, Ian Clarke, Joanne Fielding, Philip Howard, Conor Jamieson, Siraj A Misbah and 9 more

Abstract readReview
In one paragraph

Review in JAC-antimicrobial resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Catherine E PorterDental Translational and Clinical Research Unit, School of Dentistry, University of Leeds, Leeds, UK.ORCID https://orcid.org/0009-0008-9208-4761
Caity RolestonNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Claire BethunePeninsula Immunology and Allergy Service, University Hospitals Plymouth NHS Trust, Plymouth, UK.
Jenny BoardsPPIE Contributor, Dental Translational and Clinical Research Unit, part of the NIHR Leeds Clinical Research Facility, School of Dentistry, University of Leeds, Leeds, UK.
Colin S BrownAntimicrobial Resistance & Healthcare-Associated Infections Division, UK Health Security Agency, London, UK.
Ian ClarkePPIE Contributor.
Joanne FieldingDental Translational and Clinical Research Unit, School of Dentistry, University of Leeds, Leeds, UK.
Philip HowardRegional Antimicrobial Stewardship Lead, NHS England, North-East and Yorkshire, Newcastle, UK.ORCID https://orcid.org/0000-0002-5096-0240
Conor JamiesonMedical Directorate, NHS England (Midlands), Birmingham, UK.
Siraj A MisbahDepartment of Clinical Immunology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Andrew C MossEgton Medical Information Systems Limited (t/a Optum), Fulford Grange, Micklefield Lane, Rawdon, Leeds, UK.
Sue H PavittDental Translational and Clinical Research Unit, School of Dentistry, University of Leeds, Leeds, UK.
Neil PowellPharmacy Department, Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, UK.ORCID https://orcid.org/0000-0002-6113-9810
Louise SavicDepartment of Anaesthesia, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Sinisa SavicLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID https://orcid.org/0000-0001-7910-0554
Mamidipudi Thirumala KrishnaDepartment of Immunology and Immunotherapy, School of Infection, Inflammation and Immunology, University of Birmingham, Birmingham, UK.
Sarah Tonkin-CrineNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0003-4470-1151
Iestyn WilliamsHealth Services Management Centre, University of Birmingham, Edgbaston, Birmingham, UK.ORCID https://orcid.org/0000-0002-9462-9488
Jonathan A T SandoeHealthcare Associated Infection Group, Leeds Institute of Medical Research, School of Medicine, University of Leeds, Leeds, UK.ORCID https://orcid.org/0000-0003-0193-8677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, there is increasing evidence that incorrect penicillin allergy labels negatively affect patient outcomes, antibiotic prescribing and antimicrobial resistance, leading to growing concern about this patient safety issue and how to resolve it. While many millions of patients worldwide have incorrect penicillin allergy labels, there are too few specialist allergists and a lack of 'point-of-care' tests to address this problem. Numerous research studies now provide evidence of the feasibility and importance of widening access to penicillin allergy assessment. Researchers from two UK-based studies (SPACE and ALABAMA), in collaboration with key stakeholders including patient representatives, gave their views to shape a high-level implementation plan to facilitate widening access to penicillin allergy assessment in the UK. This Viewpoint describes the basis of the implementation plan and summarizes the key actions required for successful delivery. While the plan is intended for the UK, we hope to promote international shared learning and collaboration to address this global problem informed by the UK context.

Identifiers

PMID41510201
PMCPMC12776011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.