Evidence map›Paper›PMID 41510706›Full record

ReviewBioscience reports2026

Circulating tumor cells and circulating tumor microemboli: role in venous thromboembolism in oncologic patients.

Anna Paula Carreta Ruano, Jacqueline Aparecida Torres, Ludmilla Thomé Domingos Chinen

Abstract readReview
In one paragraph

Review in Bioscience reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna Paula Carreta RuanoHcor, São Paulo, Paraíso, São Paulo-SP, Brazil (Rua Desembargador Eliseu Guilherme 147), Brazil.
Jacqueline Aparecida TorresHcor, São Paulo, Paraíso, São Paulo-SP, Brazil (Rua Desembargador Eliseu Guilherme 147), Brazil.
Ludmilla Thomé Domingos ChinenHcor, São Paulo, Paraíso, São Paulo-SP, Brazil (Rua Desembargador Eliseu Guilherme 147), Brazil.ORCID 0000-0001-7890-8420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thromboembolism (VTE) is one of the most frequent and serious complications in cancer patients, contributing significantly to morbidity, mortality, and increased healthcare burden. Circulating tumor cells (CTCs) and circulating tumor microemboli (CTMs), components of the liquid biopsy, have emerged not only as biomarkers of disease progression and therapeutic resistance but also as potential contributors to prothrombotic states in oncologic patients. In this review, we explore the biological and clinical relationships between CTCs/CTMs and the development of VTE, highlighting mechanistic insights involving tumor-platelet interactions, immune evasion, and endothelial dysfunction. We also discuss recent findings on the prognostic value of CTCs and CTMs for thromboembolic risk stratification, as well as technological advances in their detection. Understanding the role of these circulating tumor-derived elements may open new perspectives for personalized prevention and management of thromboembolic events in cancer patients.

Indexed as

NeoplasmsNeoplastic Cells, CirculatingVenous ThromboembolismBiomarkers, TumorHumansLiquid BiopsyPrognosisBiomarkers, Tumorbiomarkerscancercirculating tumor cellscirculating tumor microemboliliquid biopsythrombosisvenous thromboembolism

Identifiers

PMID41510706
PMCPMC12871040

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.