Evidence mapPaperPMID 41511307Full record

ReviewCells2025

Microbiota-Mediated Bile Acid Metabolism as a Mechanistic Framework for Precision Nutrition in Gastrointestinal and Metabolic Diseases.

Suna Kang, Do-Youn Jeong, Jeowon Seo, James W Daily, Sunmin Park

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Elevated neurofilament light chain (NfL) in blood and CSF as a biomarker for Parkinson's disease cognitive impairment: A meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Review
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  4. Review
  5. Gut microbiota and disease.Essays in biochemistry · 2026
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suna KangDepartment of Food and Nutrition, Obesity/Diabetes Research Center, College of Biohealth Science, Hoseo University, Asan-si 31499, Republic of Korea.
Do-Youn JeongMicrobial Institute for Fermentation Industry, Sunchang-gun 56048, Republic of Korea.
Jeowon SeoMicrobial Institute for Fermentation Industry, Sunchang-gun 56048, Republic of Korea.
James W DailyR&D, Daily Manufacturing, Rockwell, NC 28138, USA.ORCID 0000-0002-2536-2847
Sunmin ParkDepartment of Food and Nutrition, Obesity/Diabetes Research Center, College of Biohealth Science, Hoseo University, Asan-si 31499, Republic of Korea.ORCID 0000-0002-6092-8340

Funding

National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT RS-2023-00208567
6 · The paper itself

Abstract

Gut microbiota play a central role in shaping bile acid (BA) metabolism through community-specific capacities for deconjugation, dehydroxylation, and other transformation reactions. Distinct microbiome compositional patterns-often referred to as enterotype-like clusters-correspond to reproducible functional profiles that generate unique BA metabolic signatures with relevance for metabolic and gastrointestinal health. This narrative review synthesizes current evidence describing the interplay between microbial composition, BA metabolism, and metabolic dysfunction. A structured literature search was conducted in PubMed, Web of Science, EMBASE, and Scopus using predefined keywords related to bile acids, microbiome composition, metabolic disorders, and enterotypes. Studies were screened for human clinical relevance and mechanistic insights into BA-microbiome interactions. Across the evidence base,

Indexed as

Bile Acids and SaltsGastrointestinal DiseasesGastrointestinal MicrobiomeMetabolic DiseasesPrecision MedicineAnimalsHumansBile Acids and Saltsbile acidsenterotypesgut microbiotahost genetic polymorphism

Identifiers

PMID41511307
PMCPMC12785842

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.