Evidence mapPaperPMID 41511326Full record

ReviewCells2025

Non-Motor Symptoms: The Hidden Face of Parkinson's Disease.

Carlo Cattaneo, Andrea Fabbrini, Daniele Belvisi, Flavia Aiello, Francesco Marchet, Giovanni Fabbrini

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. What's in a name? reframing advanced Parkinson's disease as a multidimensional state.Journal of neural transmission (Vienna, Austria : 1996) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlo CattaneoMedical Department, Zambon SpA, 20091 Bresso, Italy.ORCID 0009-0006-7810-4514
Andrea FabbriniNeurology Department, San Giovanni Hospital, 00153 Rome, Italy.ORCID 0000-0003-3906-0230
Daniele BelvisiDepartment Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.
Flavia AielloDepartment Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.
Francesco MarchetNeurology Department, IRCSS Neuromed, 86077 Pozzilli, Italy.ORCID 0009-0002-8481-2155
Giovanni FabbriniDepartment Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-motor symptoms (NMSs) of Parkinson's disease (PD) were recognized by James Parkinson himself about 200 years ago and are now considered to be an integral part of PD, significantly contributing to the deterioration of patients' quality of life. Although awareness of NMSs is growing, and several scientific societies now have dedicated non-motor study groups, the NMS burden is still the hidden face of PD and in most cases, clinicians' views are focused on the motor symptoms alone. The literature was reviewed using several databases and scientific journals; this review provides a comprehensive description of the most common NMSs in PD, their clinical phenotype, social impact, diagnosis, and therapeutic management. Early recognition of these features may lead to more prompt and effective treatment and may help to better understand patients' needs.

Indexed as

Parkinson DiseaseHumansQuality of Lifemanagementnon-motor symptomsParkinson’s diseasequality of life

Identifiers

PMID41511326
PMCPMC12785109

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.